SCHEMBL2761576

SCHEMBL2761576

CC(=O)Oc1c(C(=O)O)ccc2ccccc12

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
WDR5 P61964 1/20 0.56
LDHA P00338 1/20 0.54
KDM4E B2RXH2 6/20 0.54
HPGD P15428 5/20 0.54
HSD17B10 Q99714 4/20 0.54
ALDH1A1 P00352 4/20 0.54
MAPK1 P28482 1/20 0.54
NR4A1 P22736 1/20 0.50
NR4A2 P43354 1/20 0.50
NR4A3 Q92570 1/20 0.50
ESR1 P03372 1/20 0.50
ITGB3 P05106 1/20 0.50
ITGA2B P08514 1/20 0.50
HMGB1 P09429 1/20 0.50
TSHR P16473 1/20 0.50
GGT1 P19440 1/20 0.50
PTGS1 P23219 1/20 0.50
PTGS2 P35354 1/20 0.50
BLM P54132 1/20 0.50
NAPRT Q6XQN6 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL536341 0.98 WDR5 (0.54) WDR5LDHAKDM4EHPGDHSD17B10
SCHEMBL6621295 0.88 HPGD (0.46) WDR5LDHAKDM4EHPGDHSD17B10
SCHEMBL29963092 0.86 KDM4E (0.50) WDR5LDHAKDM4EHPGDHSD17B10
SCHEMBL11982347 0.84 WDR5 (0.50) WDR5LDHAKDM4EHPGDHSD17B10
Zinc Ion SCHEMBL536340 0.84 HPGD (0.43) WDR5LDHAKDM4EHPGDHSD17B10
SCHEMBL8107317 0.83 KDM4E (0.50) KDM4EHPGDHSD17B10ALDH1A1MAPK1
SCHEMBL1671110 0.83 CYP1A1 (0.64) WDR5LDHAKDM4EHPGDALDH1A1
SCHEMBL10866231 0.81 WDR5 (0.50) WDR5LDHAKDM4EHPGDALDH1A1
SCHEMBL20594147 0.81 WDR5 (0.53) WDR5LDHAKDM4EHPGDALDH1A1
SCHEMBL28518059 0.80 PTPN1 (0.51) KDM4EHPGDHSD17B10ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1203473-A None JP disclosed
EP-4255956-A1 LIQUID CRYSTALLINE POLYESTERS (LCP) AND THERMOPLASTIC COMPOSITIONS HAVING LOW DIELECTRIC CONSTANT (DK) AND DISSIPATION FACTOR (DF) Solvay Specialty Polymers USA, LLC (US) 2023-10-11 EP disclosed
WO-2023025775-A1 SOLUBLE LIQUID CRYSTALLINE POLYESTERS HAVING LOW DIELECTRIC CONSTANT AND DISSIPATION FACTOR, AND ARTICLES CONTAINING SUCH POLYMERS SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2023-03-02 WO disclosed
WO-2022117518-A1 LIQUID CRYSTALLINE POLYESTERS (LCP) AND THERMOPLASTIC COMPOSITIONS HAVING LOW DIELECTRIC CONSTANT (DK) AND DISSIPATION FACTOR (DF) SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2022-06-09 WO disclosed
CN-105636996-B Method for producing polyvinyl alcohol resin and polyvinyl alcohol resin obtained thereby 日本瓦姆&珀巴尔株式会社 2018-05-29 CN disclosed
US-8354359-B2 Heat-sensitive adhesive agent and heat-sensitive adhesive sheet RICOH COMPANY, LTD. (JP) 2013-01-15 US disclosed
US-8324405-B2 Chromene derivatives and use thereof as HIF hydroxylase activity inhibitors FIBROGEN, INC. (US) 2012-12-04 US disclosed
US-20100331400-A1 CHROMENE DERIVATIVES AND USE THEREOF AS HIF HYDROXYLASE ACTIVITY INHIBITORS FIBROGEN, INC. 2010-12-30 US disclosed
US-7811661-B2 Heat-sensitive adhesive material RICOH COMPANY, LTD. (JP) 2010-10-12 US disclosed
WO-2009100250-A1 CHROMENE DERIVATIVES AND USE THEREOF AS HIF HYDROXYLASE ACTIVITY INHIBITORS FIBROGEN, INC. (US) 2009-08-13 WO disclosed
EP-0764548-A2 Thermosensitive recording adhesive label sheet Ricoh Company, Ltd (JP) 1997-03-26 EP disclosed
EP-0612628-B1 Thermosensitive recording material using phthalic acid derivatives RICOH KK (JP) 1996-07-10 EP disclosed
US-5482912-A DEVELOPERS, THERMAL PRINTING, INTERMEDIATE LAYER OF THERMOPLASTIC HOLLOW SPHERES RICOH COMPANY, LTD. (JP) 1996-01-09 US disclosed
EP-0612628-A1 Thermosensitive recording material using phthalic acid derivatives Ricoh Company, Ltd (JP) 1994-08-31 EP disclosed
US-5306687-A Optical recording media comprising p'-methylphenyl p-chlorobenzoate as thermosensitizers RICOH COMPANY, LTD. (JP) 1994-04-26 US disclosed
EP-0396955-A2 Liquid crystal polyester resin composition improved in fluidity SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-11-14 EP disclosed
JP-H01203473-A RUBBER COMPOSITION FOR COATING STEEL CORD YOKOHAMA RUBBER CO LTD:THE 1989-08-16 JP disclosed
EP-0273423-A2 Aromatic polyesters and their use KURARAY CO., LTD. (JP) 1988-07-06 EP disclosed
US-4692546-A OXIDATION OF KETONE, MANGANESE CATIONS CELANESE CORPORATION (US) 1987-09-08 US disclosed
EP-0170483-A2 Process for producing acyloxy aromatic carboxylic acid CELANESE CORPORATION (US) 1986-02-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100331400-A1 CHROMENE DERIVATIVES AND USE THEREOF AS HIF HYDROXYLASE ACTIVITY INHIBITORS HIF1AN, HIF1A, EGLN2 WDR5 3580/4885LDHA 72/4885KDM4E 550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.