SCHEMBL28518059

SCHEMBL28518059

CC(=O)Oc1c(C(=O)O)ccc2cc(C(=O)O)ccc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.51
KDM4E B2RXH2 7/20 0.49
ALDH1A1 P00352 5/20 0.49
TSHR P16473 3/20 0.49
GAA P10253 2/20 0.49
RAB9A P51151 1/20 0.49
HSD17B10 Q99714 4/20 0.46
HPGD P15428 4/20 0.46
MAPK1 P28482 1/20 0.46
ACE2 Q9BYF1 2/20 0.43
CFD P00746 2/20 0.41
MAPT P10636 1/20 0.41
USP2 O75604 1/20 0.39
CYP2C19 P33261 1/20 0.39
LMNA P02545 1/20 0.39
ESR1 P03372 1/20 0.39
ITGB3 P05106 1/20 0.39
ITGA2B P08514 1/20 0.39
HMGB1 P09429 1/20 0.39
GGT1 P19440 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8764974 0.84 PTPN1 (0.50) PTPN1KDM4EALDH1A1TSHRGAA
SCHEMBL2761576 0.80 WDR5 (0.56) KDM4EALDH1A1TSHRGAAHSD17B10
SCHEMBL10835777 0.79 TSHR (0.61) PTPN1KDM4EALDH1A1TSHRGAA
SCHEMBL29963092 0.79 KDM4E (0.50) KDM4EALDH1A1TSHRGAAHSD17B10
SCHEMBL536341 0.78 WDR5 (0.54) KDM4EALDH1A1TSHRGAAHSD17B10
SCHEMBL10630715 0.77 TP53 (0.51) PTPN1TSHR
SCHEMBL11801334 0.77 PTPN1 (0.50) PTPN1KDM4EHSD17B10ACE2MAPT
SCHEMBL10835153 0.77 KDM4E (0.63) PTPN1KDM4EALDH1A1TSHRGAA
SCHEMBL9711114 0.76 ALDH1A1 (0.51) PTPN1KDM4EALDH1A1TSHRGAA
SCHEMBL2749203 0.76 PTPN1 (0.59) PTPN1KDM4EALDH1A1RAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112339384-B Optical polyester film and preparation method thereof 合肥乐凯科技产业有限公司 2022-08-16 CN claimed
CN-112339384-A Optical polyester film and preparation method thereof 合肥乐凯科技产业有限公司 2021-02-09 CN claimed
CN-112339384-B Optical polyester film and preparation method thereof 合肥乐凯科技产业有限公司 2022-08-16 CN disclosed
CN-112339384-A Optical polyester film and preparation method thereof 合肥乐凯科技产业有限公司 2021-02-09 CN disclosed