Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27569299 | 0.84 | L3MBTL3 (0.56) | GAAHTTCA12CA1CA2 | |
| SCHEMBL27634694 | 0.84 | TPSAB1 (0.48) | HRH3KCNH2CHRM2 | |
| Hydrochloric Acid SCHEMBL4794010 | 0.83 | L3MBTL3 (0.54) | GAAHTTCA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL4772777 | 0.80 | GAA (0.61) | HRH3GAAHTTCA12CA1 | |
| SCHEMBL3916721 | 0.77 | HRH3 (0.72) | HRH3CHRNA7EPHX2 | |
| SCHEMBL12736124 | 0.77 | TPSAB1 (0.53) | HRH3KCNH2 | |
| SCHEMBL4773726 | 0.76 | GBA1 (0.51) | — | |
| SCHEMBL1177694 | 0.75 | HRH3 (0.89) | HRH3CHRNA7 | |
| SCHEMBL20245324 | 0.75 | HRH3 (0.69) | HRH3CHRNA7EPHX2 | |
| SCHEMBL4237305 | 0.75 | HRH3 (0.61) | HRH3KCNH2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100558718-C | Piperazinyl and diazacyclo heptyl benzene methane amide and thiobenzamide | JANSSEN PHARMACEUTICA NV (BE) | 2009-11-11 | — | — | CN | disclosed |
| CN-1729180-A | Piperazinyl and diazapanyl benzamides and benzthioamides | JANSSEN PHARMACEUTICA NV (BE) | 2006-02-01 | — | — | CN | disclosed |