Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6368377 | 0.86 | ALDH1A1 (0.42) | ALDH1A1HPGDKDM4EHSD17B10GAA | |
| SCHEMBL24821171 | 0.83 | PLCG1 (0.47) | ALDH1A1HPGDKDM4EHSD17B10F2 | |
| SCHEMBL10412004 | 0.82 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4EHSD17B10F2 | |
| SCHEMBL8563130 | 0.82 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4EHSD17B10F2 | |
| SCHEMBL29608063 | 0.81 | KDM4E (0.50) | ALDH1A1KDM4EHSD17B10GAAMEN1 | |
| SCHEMBL288855 | 0.81 | KDM4E (0.50) | ALDH1A1KDM4EHSD17B10GAAMEN1 | |
| SCHEMBL198219 | 0.81 | KDM4E (0.50) | ALDH1A1KDM4EHSD17B10GAAMEN1 | |
| SCHEMBL146376 | 0.81 | KDM4E (0.50) | ALDH1A1KDM4EHSD17B10GAAMEN1 | |
| SCHEMBL9087816 | 0.81 | ALDH1A1 (0.43) | ALDH1A1HPGDKDM4EHSD17B10F2 | |
| SCHEMBL9088372 | 0.81 | ALDH1A1 (0.43) | ALDH1A1HPGDKDM4EHSD17B10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111153805-A | Cinacalcet intermediate, and synthesis method and application thereof | 南京红杉生物科技有限公司 | 2020-05-15 | — | — | CN | claimed |
| CN-104861046-A | N-methyl cyclic pentapeptide compound and synthesis method and application thereof | UNIV HEBEI SCIENCE & TECH | 2015-08-26 | — | — | CN | claimed |
| CN-113121648-B | N-methyl cyclic pentapeptide compound and synthesis method and application thereof | 河北科技大学 | 2022-07-01 | — | — | CN | disclosed |
| CN-112851536-B | Method for constructing amide bond by clicking pyrimidine condensing agent and application of method in amide and polypeptide synthesis | 兰州大学 | 2022-02-25 | — | — | CN | disclosed |
| CN-113121648-A | N-methyl cyclic pentapeptide compound and synthesis method and application thereof | 河北科技大学 | 2021-07-16 | — | — | CN | disclosed |
| CN-112851536-A | Method for constructing amide bond by clicking pyrimidine condensing agent and application of method in amide and polypeptide synthesis | 兰州大学 | 2021-05-28 | — | — | CN | disclosed |
| CN-111153805-A | Cinacalcet intermediate, and synthesis method and application thereof | 南京红杉生物科技有限公司 | 2020-05-15 | — | — | CN | disclosed |
| CN-111153805-A | Cinacalcet intermediate, and synthesis method and application thereof | 南京红杉生物科技有限公司 | 2020-05-15 | — | — | CN | disclosed |
| CN-104861046-A | N-methyl cyclic pentapeptide compound and synthesis method and application thereof | UNIV HEBEI SCIENCE & TECH | 2015-08-26 | — | — | CN | disclosed |
| CN-1612887-A | Phosphino-aminophosphines | EASTMAN CHEM CO (US) | 2005-05-04 | — | — | CN | disclosed |