Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.60 |
| ▸ | PRKCG | P05129 | 2/20 | 0.53 |
| ▸ | PRKCB | P05771 | 2/20 | 0.53 |
| ▸ | PRKCA | P17252 | 2/20 | 0.53 |
| ▸ | PRKCH | P24723 | 2/20 | 0.53 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.53 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.53 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 6/20 | 0.48 |
| ▸ | DRD2 | P14416 | 5/20 | 0.48 |
| ▸ | DRD3 | P35462 | 5/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.47 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.47 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4989734 | 0.88 | HTR6 (0.55) | HTR6PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL4990643 | 0.79 | HTR6 (0.58) | HTR6PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL4988531 | 0.77 | HTR6 (0.56) | HTR6PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL13915330 | 0.77 | PRKCG (0.55) | HTR6PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL4074930 | 0.75 | HTR6 (1.00) | HTR6PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL5625905 | 0.74 | ADORA1 (0.78) | NPSR1KDM4EADORA1SERPINE1 | |
| SCHEMBL12486470 | 0.73 | KDM4E (0.69) | HTR6NPSR1KDM4E | |
| SCHEMBL588318 | 0.73 | PRKCG (0.55) | PRKCGPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL11770132 | 0.72 | KDM4E (0.64) | NPSR1KDM4E | |
| SCHEMBL15856599 | 0.71 | KDM4E (0.56) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1639152-A | Pyrrole-2, 5-dione derivatives and their use as GSK-3 inhibitors | LILLY CO ELI (US) | 2005-07-13 | — | — | CN | disclosed |