Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.44 |
| ▸ | DRD3 | P35462 | 10/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.39 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4676940 | 0.73 | DRD2 (0.44) | DRD2DRD3TSHRCYP2D6NFKB1 | |
| SCHEMBL29683775 | 0.73 | DRD2 (0.50) | DRD2DRD3TSHRCYP2D6NFKB1 | |
| SCHEMBL8688588 | 0.72 | DRD2 (0.51) | DRD2DRD3TSHRCYP2D6NFKB1 | |
| SCHEMBL4875328 | 0.70 | DRD2 (0.67) | DRD2DRD3TSHRCYP2D6NFKB1 | |
| SCHEMBL4699946 | 0.69 | DRD2 (0.45) | DRD2DRD3TSHRCYP2D6NFKB1 | |
| SCHEMBL31523251 | 0.67 | DRD2 (0.73) | DRD2DRD3TSHRCYP2D6NFKB1 | |
| SCHEMBL2227921 | 0.66 | DRD2 (0.71) | DRD2DRD3TSHRCYP2D6NFKB1 | |
| SCHEMBL4674179 | 0.66 | DRD2 (0.56) | DRD2DRD3TSHRCYP2D6NFKB1 | |
| SCHEMBL21358194 | 0.65 | DRD2 (0.47) | DRD2DRD3TSHRCYP2D6NFKB1 | |
| SCHEMBL31332598 | 0.65 | DRD2 (0.51) | DRD2DRD3TSHRCYP2D6NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1617718-A | N-aryl-N'-arylcycloalkyl-urea derivatives as MCH antagonists for the treatment of obesity | SCHERING CORP (US) | 2005-05-18 | — | — | CN | disclosed |