SCHEMBL2761872

SCHEMBL2761872

C/C=C\C1NC(C)(C)C(=O)O1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1810452 0.78
SCHEMBL6112974 0.73
SCHEMBL6112965 0.63
SCHEMBL3325238 0.62 ALDH1A1 (0.36)
SCHEMBL6466032 0.60
SCHEMBL12970866 0.58 CRBN (0.30)
SCHEMBL6130351 0.58
SCHEMBL19442183 0.57 CYP2D6 (0.30)
SCHEMBL28891398 0.57
SCHEMBL28376102 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3015103-B2 2000-03-06 JP claimed
EP-0560916-B1 Method of molding of silicon-containing contact lenses BAUSCH & LOMB (US) 1997-02-05 EP claimed
EP-0611379-B1 WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS FOR THEIR MANUFACTURE BAUSCH & LOMB (US) 1996-05-29 EP claimed
US-5352714-A Curing and hydrating an unsaturated oxazolone monomer, a polysiloxane having acrylated end groups and an unsaturated monomer; contact lenses BAUSCH & LOMB INCORPORATED (US) 1994-10-04 US claimed
EP-0611380-A1 WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS FOR THEIR MANUFACTURE. BAUSCH & LOMB (US) 1994-08-24 EP claimed
EP-0611379-A1 WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS FOR THEIR MANUFACTURE. BAUSCH & LOMB (US) 1994-08-24 EP claimed
EP-0338656-B1 Polymeric silicone-based materials with high oxygen permeability BAUSCH & LOMB (US) 1994-03-02 EP claimed
US-5274008-A Using a mold surface having improved wettability made of a copolymer of an acrylic mononitrile and a monomer that enhances melt processability; contact lenses BAUSCH & LOMB INCORPORATED (US) 1993-12-28 US claimed
EP-0560916-A1 MOLD MATERIALS FOR SILICONE CONTAINING LENS MATERIALS. BAUSCH & LOMB (US) 1993-09-22 EP claimed
WO-1993009155-A1 WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS FOR THEIR MANUFACTURE BAUSCH & LOMB INCORPORATED (US) 1993-05-13 WO claimed
WO-1993009154-A1 WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS FOR THEIR MANUFACTURE BAUSCH & LOMB INCORPORATED (US) 1993-05-13 WO claimed
WO-1992009421-A2 MOLD MATERIALS FOR SILICONE CONTAINING LENS MATERIALS BAUSCH & LOMB INCORPORATED (US) 1992-06-11 WO claimed
EP-4646240-A1 BIOMEDICAL DEVICES HAVING A SURFACE COATING Bausch + Lomb Ireland Limited (IE) 2025-11-12 EP disclosed
US-20240240047-A1 BIOMEDICAL DEVICES HAVING A SURFACE COATING JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT 2024-07-18 US disclosed
WO-2024146878-A1 BIOMEDICAL DEVICES HAVING A SURFACE COATING BAUSCH + LOMB IRELAND LIMITED (IE) 2024-07-11 WO disclosed
EP-2370113-B1 PACKAGING SOLUTIONS BAUSCH & LOMB (US) 2013-12-11 EP disclosed
US-4910277-A Blend of polysiloxane and an interior wetting agent BAUSCH & LOMB INCORPORATED 1990-03-20 US disclosed
EP-0338656-A2 Polymeric silicone-based materials with high oxygen permeability BAUSCH &amp; LOMB INCORPORATED (US) 1989-10-25 EP disclosed
EP-0328340-A2 Hydrophilic oxygen permeable polymers BAUSCH &amp; LOMB INCORPORATED (US) 1989-08-16 EP disclosed
US-4810764-A CONTACT LENSES BAUSCH & LOMB INCORPORATED (US) 1989-03-07 US disclosed