⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12130380 | 0.87 | KDM4E (0.33) | — | |
| SCHEMBL16280996 | 0.85 | KDM4E (0.42) | — | |
| SCHEMBL11981948 | 0.80 | KDM4E (0.39) | — | |
| SCHEMBL1578074 | 0.79 | LMNA (0.43) | — | |
| SCHEMBL24383338 | 0.79 | KDM4E (0.31) | — | |
| SCHEMBL5371148 | 0.78 | — | — | |
| SCHEMBL15001267 | 0.78 | — | — | |
| SCHEMBL10473953 | 0.77 | TDP1 (0.37) | — | |
| SCHEMBL7083891 | 0.76 | KDM4E (0.36) | — | |
| SCHEMBL22327484 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107567445-A | It can be used as 2 phenyl 3H imidazos [4,5 B] pyridine derivates of mammal EGFR-TK ROR1 activities inhibitor | 坎塞拉有限公司 | 2018-01-09 | — | — | CN | claimed |
| US-7235258-B1 | Sustained-release formulations for treating CNS-mediated disorders | NPS PHARMACEUTICALS, INC. (US) | 2007-06-26 | — | — | US | claimed |
| EP-1576962-A1 | Composition comprising isovaleramide and ibuprofen | NPS PHARMACEUTICALS, INC. (US) | 2005-09-21 | — | — | EP | claimed |
| US-20040072900-A1 | Treating a variety of pathological conditions, including spasticity and convulsions, by effecting a modulation of CNS activity with isovaleramide, isovaleric acid, or a related compound | NPS PHARMACEUTICALS | 2004-04-15 | — | — | US | claimed |
| EP-1225888-A2 | SUSTAINED-RELEASE FORMULATIONS FOR TREATING CNS-MEDIATED DISORDERS | NPS PHARMACEUTICALS, INC. (US) | 2002-07-31 | — | — | EP | claimed |
| US-6383527-B1 | FOR TREATMENT OF ACUTE MUSCULAR ACHES, STRAINS, AND SPRAINS WHICH OCCUR FROM A LOCALIZED, EXTERNAL INSULT TO A PARTICULAR MUSCLE OR MUSCLE GROUP | NPS PHARMACEUTICALS, INC. | 2002-05-07 | — | — | US | claimed |
| WO-2001028516-A2 | SUSTAINED-RELEASE FORMULATIONS FOR TREATING CNS-MEDIATED DISORDERS | NPS PHARMACEUTICALS, INC. (US) | 2001-04-26 | — | — | WO | claimed |
| EP-1059930-A1 | COMPOSITIONS COMPRISING VALERIAN EXTRACTS, ISOVALERIC ACID OR DERIVATIVES THEREOF WITH A NSAID | NPS PHARMACEUTICALS, INC. (US) | 2000-12-20 | — | — | EP | claimed |
| WO-1999044623-A1 | COMPOSITIONS COMPRISING VALERIAN EXTRACTS, ISOVALERIC ACID OR DERIVATIVES THEREOF WITH A NSAID | NPS PHARMACEUTICALS, INC. (US) | 1999-09-10 | — | — | WO | claimed |
| EP-0318933-A2 | Psychotropic acyclic amide derivatives, a process for preparing them and pharmaceutical compositions | Bristol-Myers Squibb Company (US) | 1989-06-07 | — | — | EP | claimed |
| CN-116568763-B | Wavelength selective absorption filter and display device | 富士胶片株式会社 | 2025-05-13 | — | — | CN | disclosed |
| US-20240091184-A1 | MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. | 2024-03-21 | — | — | US | disclosed |
| CN-116568763-A | Wavelength selective absorption filter and display device | 富士胶片株式会社 | 2023-08-08 | — | — | CN | disclosed |
| CN-116370448-A | Modulators of SESTRIN-GATOR2 interactions and uses thereof | 纳维托制药有限公司 | 2023-07-04 | — | — | CN | disclosed |
| US-11679090-B2 | Modulators of Sestrin-GATOR2 interaction and uses thereof | NAVITOR PHARMACEUTICALS, INC. (US) | 2023-06-20 | — | — | US | disclosed |
| EP-0668852-A1 | SUBSTITUTED ORTHO-ETHENYL-PHENYL ACETIC ACID DERIVATIVES | BASF Aktiengesellschaft (DE) | 1995-08-30 | — | — | EP | disclosed |
| CN-1098713-A | The ortho-ethenylphenylacetic acid derivatives that replaces | BASF AG (DE) | 1995-02-15 | — | — | CN | disclosed |
| EP-0414058-B1 | Carboxylic acid derivatives | BASF AG (DE) | 1994-06-15 | — | — | EP | disclosed |
| WO-1994011334-A1 | SUBSTITUTED ORTHO-ETHENYL-PHENYL ACETIC ACID DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1994-05-26 | — | — | WO | disclosed |
| EP-0546409-A1 | Method for the preparation of tetrahydropyrancarboxylic esters | BASF Aktiengesellschaft (DE) | 1993-06-16 | — | — | EP | disclosed |