Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CPT2 | P23786 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | BHMT | Q93088 | 3/20 | 0.31 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18760169 | 0.82 | FFAR1 (0.54) | FDPSTDP1FFAR1CPT2SMPD1 | |
| SCHEMBL16280996 | 0.81 | KDM4E (0.42) | LMNAHSD17B10FDPSTDP1FFAR1 | |
| SCHEMBL21626032 | 0.80 | FFAR1 (0.39) | LMNAHSD17B10TDP1FFAR1CPT2 | |
| SCHEMBL5521030 | 0.80 | FFAR1 (0.62) | FDPSTDP1FFAR1CPT2KDM4E | |
| SCHEMBL276192 | 0.79 | — | — | |
| SCHEMBL11566635 | 0.79 | TDP1 (0.42) | LMNAHSD17B10FDPSTDP1FFAR1 | |
| SCHEMBL21625335 | 0.78 | LMNA (0.42) | LMNAHSD17B10FDPSTDP1ALOX15 | |
| SCHEMBL1409491 | 0.77 | TSHR (0.43) | LMNAHSD17B10FDPSTDP1FFAR1 | |
| SCHEMBL974936 | 0.77 | FFAR1 (0.65) | LMNAHSD17B10TDP1FFAR1CPT2 | |
| SCHEMBL1784497 | 0.77 | TDP1 (0.41) | LMNAHSD17B10FDPSTDP1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160443-A1 | COMPOUNDS USEFUL FOR TREATING NEUROLOGICAL DISORDERS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2010-06-24 | — | — | US | claimed |
| US-20090182048-A1 | Compounds Useful For Treating Neurological Disorders | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2009-07-16 | — | — | US | claimed |
| WO-2009018132-A9 | METHODS AND SYSTEMS FOR ATTENUATING THE TOLERANCE RESPONSE TO A DRUG | NEUROVISTA CORP (US) | 2009-06-25 | — | — | WO | claimed |
| WO-2009018132-A2 | METHODS AND SYSTEMS FOR ATTENUATING THE TOLERANCE RESPONSE TO A DRUG | NEUROVISTA CORPORATION (US) | 2009-02-05 | — | — | WO | claimed |
| US-20090030403-A1 | Methods and Systems for Attenuating the Tolerance Response to a Drug | CYBERONICS, INC. | 2009-01-29 | — | — | US | claimed |
| US-20060004098-A1 | Compounds useful for treating neurological disorders | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-01-05 | — | — | US | claimed |
| US-6969732-B2 | Propylisopropyl acetic acid and propylisopropyl acetamide stereoisomers, a method for their synthesis and pharmaceutical compositions containing them | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2005-11-29 | — | — | US | claimed |
| EP-1077926-B1 | PROPYLISOPROPYL ACETAMIDE STEREOISOMERS, A METHOD FOR THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | YISSUM RES DEV CO (IL) | 2005-02-23 | — | — | EP | claimed |
| US-20030212131-A1 | Propylisopropyl acetic acid and propylisopropyl acetamide stereoisomers, a method for their synthesis and pharmaceutical compositions containing them | BIALER MEIR (IL) | 2003-11-13 | — | — | US | claimed |
| US-6630602-B1 | Racemic propylisopropyl acetic acid and propylisopropyl acetamide and their isomers in their racemic and stereospecific forms, for use in treatment of neurological and psychotic disorders, and affective disorders and to treat | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2003-10-07 | — | — | US | claimed |
| EP-1077926-A1 | PROPYLISOPROPYL ACETIC ACID AND PROPYLISOPROPYL ACETAMIDE STEREOISOMERS, A METHOD FOR THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2001-02-28 | — | — | EP | claimed |
| WO-1999054282-A1 | PROPYLISOPROPYL ACETIC ACID AND PROPYLISOPROPYL ACETAMIDE STEREOISOMERS, A METHOD FOR THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY (IL) | 1999-10-28 | — | — | WO | claimed |
| WO-2024105084-A1 | USE OF LIPIDS CONJUGATED WITH POLY(ETHYLENE OXIDE) HAVING C1 TO C3-ALKYLOXYMETHYL SIDE CHAINS | Johannes Gutenberg-Universität Mainz (DE) | 2024-05-23 | — | — | WO | disclosed |
| US-20200318195-A1 | Bivalent Nucleic Acid Ligands and Uses Therefor | CARNEGIE MELLON UNIVERSITY | 2020-10-08 | — | — | US | disclosed |
| US-20180169099-A1 | HYDROXYLATED AND METHOXYLATED PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2018-06-21 | — | — | US | disclosed |
| EP-2483237-B1 | AMIDE DERIVATIVES OF VALPROIC ACID AND USES THEREOF | YISSUM RES DEV CO (IL) | 2016-05-11 | — | — | EP | disclosed |
| WO-1999054282-A1 | PROPYLISOPROPYL ACETIC ACID AND PROPYLISOPROPYL ACETAMIDE STEREOISOMERS, A METHOD FOR THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY (IL) | 1999-10-28 | — | — | WO | disclosed |
| WO-1999054282-A1 | PROPYLISOPROPYL ACETIC ACID AND PROPYLISOPROPYL ACETAMIDE STEREOISOMERS, A METHOD FOR THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY (IL) | 1999-10-28 | — | — | WO | disclosed |
| EP-0546409-B1 | Method for the preparation of tetrahydropyrancarboxylic esters | BASF AG (DE) | 1998-10-21 | — | — | EP | disclosed |
| EP-0546409-A1 | Method for the preparation of tetrahydropyrancarboxylic esters | BASF Aktiengesellschaft (DE) | 1993-06-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212131-A1 | Propylisopropyl acetic acid and propylisopropyl acetamide stereoisomers, a method for their synthesis and pharmaceutical compositions containing them | ADCYAP1R1, GRIN2A, PTGER1 | LMNA 3641/4885HSD17B10 792/4885FDPS 329/4885 |
| US-20060004098-A1 | Compounds useful for treating neurological disorders | GAP43, CLN6, NLN | LMNA 1338/4885HSD17B10 1469/4885FDPS 350/4885 |
| US-20090182048-A1 | Compounds Useful For Treating Neurological Disorders | GAP43, CLN6, NLN | LMNA 1338/4885HSD17B10 1469/4885FDPS 350/4885 |
| US-20100160443-A1 | COMPOUNDS USEFUL FOR TREATING NEUROLOGICAL DISORDERS | GAP43, CLN6, NLN | LMNA 1338/4885HSD17B10 1469/4885FDPS 350/4885 |
| US-20180169099-A1 | HYDROXYLATED AND METHOXYLATED PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS | AKT1, AKT2, AKT1S1 | LMNA 3606/4885HSD17B10 880/4885FDPS 680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.