Acetic Acid

Acetic Acid

SCHEMBL2761971

CC(=O)O.COCCN(C)C

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.48
CHRM4 P08173 1/20 0.48
CHRM5 P08912 1/20 0.48
CHRM1 P11229 1/20 0.48
CHRNB2 P17787 1/20 0.48
CHRM3 P20309 1/20 0.48
CHRNA4 P43681 1/20 0.48
ALDH1A1 P00352 7/20 0.41
DNM1 Q05193 1/20 0.38
PIK3CD O00329 1/20 0.38
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
SMN1; SMN2 Q16637 3/20 0.36
PHLPP2 Q6ZVD8 1/20 0.36
KDM4E B2RXH2 4/20 0.36
GAA P10253 1/20 0.36
USP2 O75604 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycolic Acid SCHEMBL5031495 0.86 CHRM2 (0.45) CHRM2CHRM4CHRM5CHRM1CHRNB2
Propionic Acid SCHEMBL5026941 0.86 FFAR3 (0.46) CHRM2CHRM4CHRM5CHRM1CHRNB2
Acetic Acid SCHEMBL5027741 0.85 PIK3CD (0.48) CHRM2CHRM4CHRM5CHRM1CHRNB2
SCHEMBL174185 0.84
Iodide SCHEMBL5017287 0.81
SCHEMBL11230541 0.81
Hydrochloric Acid SCHEMBL10570933 0.81
SCHEMBL27389859 0.79 CHRNB2 (0.39) CHRM2CHRM4CHRM5CHRM1CHRNB2
SCHEMBL27753057 0.78 CHRM2 (0.41) CHRM2CHRM4CHRM5CHRM1CHRNB2
Acetic Acid SCHEMBL27845271 0.78 CHRM1 (0.58) CHRM2CHRM4CHRM5CHRM1CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160017540-A1 PRETREATMENT AND FRACTIONATION OF LIGNOCELLULOSIC BIOMASS SUGANIT SYSTEMS, INC. 2016-01-21 US claimed
EP-2971190-A1 ALKALINE TREATMENT OF LIGNOCELLULOSIC BIOMASS Suganit Systems, Inc. (US) 2016-01-20 EP claimed
WO-2014144588-A1 ALKALINE TREATMENT OF LIGNOCELLULOSIC BIOMASS SUGANIT SYSTEMS, INC. (US) 2014-09-18 WO claimed
WO-2025034877-A2 SOLUTION SPINNING OF PROTEIN-CELLULOSIC BLEND FIBERS THE PENN STATE RESEARCH FOUNDATION (US) 2025-02-13 WO disclosed
US-20160017540-A1 PRETREATMENT AND FRACTIONATION OF LIGNOCELLULOSIC BIOMASS SUGANIT SYSTEMS, INC. 2016-01-21 US disclosed
EP-2971190-A1 ALKALINE TREATMENT OF LIGNOCELLULOSIC BIOMASS Suganit Systems, Inc. (US) 2016-01-20 EP disclosed
US-20150259571-A1 LIGNIN MEMBRANES AND COATINGS EMPIRE TECHNOLOGY DEVELOPMENT LLC 2015-09-17 US disclosed
WO-2014144588-A1 ALKALINE TREATMENT OF LIGNOCELLULOSIC BIOMASS SUGANIT SYSTEMS, INC. (US) 2014-09-18 WO disclosed
WO-2014035498-A1 LIGNIN MEMBRANES AND COATINGS EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-03-06 WO disclosed
WO-2010136105-A2 AMMONIUMCARBOXYLATES MERCK PATENT GMBH (DE) 2010-12-02 WO disclosed
CN-101316810-A Ionic liquids BIONIQS LTD (GB) 2008-12-03 CN disclosed
US-20080221361-A1 Ionic Liquids BIONIQS LIMITED (GB) 2008-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160017540-A1 PRETREATMENT AND FRACTIONATION OF LIGNOCELLULOSIC BIOMASS LCT, MGAM, ENGASE CHRM2 2693/4885CHRM4 2651/4885CHRM5 2433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.