Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 9/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5543008 | 1.00 | PTK2 (0.45) | PTK2TDP1RAB9ANPC1L3MBTL1 | |
| SCHEMBL6421351 | 0.88 | PTK2 (0.46) | PTK2TDP1RAB9ANPC1L3MBTL1 | |
| SCHEMBL14496990 | 0.86 | SYK (0.51) | PTK2TDP1RAB9ANPC1L3MBTL1 | |
| SCHEMBL5542886 | 0.85 | L3MBTL1 (0.44) | PTK2TDP1RAB9ANPC1L3MBTL1 | |
| SCHEMBL5544848 | 0.84 | PTK2 (0.45) | PTK2TDP1RAB9ANPC1L3MBTL1 | |
| SCHEMBL5543092 | 0.83 | SMN1; SMN2 (0.44) | PTK2TDP1RAB9ANPC1L3MBTL1 | |
| SCHEMBL5549087 | 0.82 | RAB9A (0.51) | PTK2TDP1RAB9ANPC1L3MBTL1 | |
| SCHEMBL5548909 | 0.82 | RAB9A (0.51) | PTK2TDP1RAB9ANPC1L3MBTL1 | |
| SCHEMBL5548889 | 0.82 | PTK2 (0.45) | PTK2TDP1RAB9ANPC1L3MBTL1 | |
| SCHEMBL5548531 | 0.81 | L3MBTL1 (0.48) | PTK2TDP1RAB9ANPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1745071-A | Novel ethylenediamine derivative | DAIICHI SEIYAKU CO (JP) | 2006-03-08 | — | — | CN | disclosed |