Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK3 | O43781 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | CDK7 | P50613 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.45 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.45 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.45 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.45 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.45 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.45 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 2/20 | 0.32 |
| ▸ | MLNR | O43193 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27620109 | 0.88 | GSK3B (0.49) | DYRK3CDK1CDK2GSK3BCDK7 | |
| SCHEMBL27657010 | 0.88 | DYRK3 (0.47) | DYRK3CDK1CDK2GSK3BCDK7 | |
| SCHEMBL27620105 | 0.84 | DYRK3 (0.46) | DYRK3CDK1CDK2GSK3BCDK7 | |
| SCHEMBL27620305 | 0.82 | DYRK3 (0.42) | DYRK3CDK1CDK2GSK3BCDK7 | |
| SCHEMBL4061528 | 0.76 | CDK2 (0.51) | DYRK3CDK1CDK2GSK3BCDK7 | |
| Hydrochloric Acid SCHEMBL4062688 | 0.75 | CDK2 (0.50) | DYRK3CDK1CDK2GSK3BCDK7 | |
| SCHEMBL27657011 | 0.74 | DYRK3 (0.47) | DYRK3CDK1CDK2GSK3BCDK7 | |
| SCHEMBL27620110 | 0.74 | CDK1 (0.47) | DYRK3CDK1CDK2GSK3BCDK7 | |
| Hydrochloric Acid SCHEMBL27641516 | 0.73 | GSK3B (0.38) | DYRK3CDK1CDK2GSK3BCDK7 | |
| SCHEMBL4067810 | 0.73 | CDK2 (0.52) | DYRK3CDK1CDK2GSK3BCDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1642938-A | Novel compounds | ASTRAZENECA AB (SE) | 2005-07-20 | — | — | CN | claimed |
| CN-1923812-A | New compounds | ASTRAZENECA AB (SE) | 2007-03-07 | — | — | CN | disclosed |
| CN-1642938-A | Novel compounds | ASTRAZENECA AB (SE) | 2005-07-20 | — | — | CN | disclosed |