Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.39 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 3/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.36 |
| ▸ | LAP3 | P28838 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | GRB2 | P62993 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27713540 | 0.84 | LDHA (0.55) | LTA4HLDHAPPARGPPARA | |
| SCHEMBL1519755 | 0.83 | GRB2 (0.45) | PTPN1SLC7A5PPARGGRB2PPARA | |
| SCHEMBL1519830 | 0.82 | CTSS (0.46) | PTPN1SLC7A5PPARGGRB2PPARA | |
| SCHEMBL7048726 | 0.81 | LDHA (0.40) | PTPN1CXCR2CXCR1KDM4EKDM4A | |
| SCHEMBL27816621 | 0.81 | SLC7A5 (0.51) | LTA4HLAP3SLC7A5 | |
| SCHEMBL1519895 | 0.81 | SLC7A5 (0.41) | PTPN1LTA4HLDHALAP3SLC7A5 | |
| SCHEMBL5966604 | 0.80 | CYP3A4 (0.50) | SLC7A5PPARGPPARA | |
| SCHEMBL27590159 | 0.80 | CYP3A4 (0.50) | SLC7A5PPARGPPARA | |
| SCHEMBL1912580 | 0.80 | CTSS (0.46) | LTA4HLDHASLC7A5PPARGPPARA | |
| SCHEMBL27656101 | 0.80 | SLC7A5 (0.40) | PTPN1LTA4HLDHALAP3SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1711239-A | Novel biaromatic compounds which activate PPARy type receptors and cosmetic/pharmaceutical compositions comprised thereof | GALDERMA RES & DEV (FR) | 2005-12-21 | — | — | CN | disclosed |