Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL27620341 | 0.98 | GCGR (0.35) | GCGRCYP19A1KMT2ANPSR1PTGS2 | |
| 1,4-Dichlorobenzene SCHEMBL27842897 | 0.86 | HSD17B10 (0.42) | KMT2ANPSR1PTGS2MEN1POLB | |
| Pyrazine SCHEMBL27608305 | 0.81 | KMT2A (0.31) | KMT2ANPSR1 | |
| Ethoxycarbonyl Group SCHEMBL27777585 | 0.81 | LMNA (0.37) | KMT2ANPSR1MEN1NPC1RAB9A | |
| Chlorobenzene SCHEMBL28088147 | 0.80 | TSHR (0.46) | KMT2ANPSR1PTGS2MEN1CASP1 | |
| Formic Acid Methyl Ester SCHEMBL27661987 | 0.79 | CYP19A1 (0.40) | GCGRCYP19A1KMT2AMEN1NPC1 | |
| Ethoxycarbonyl Group SCHEMBL27750267 | 0.79 | KMT2A (0.53) | KMT2ANPSR1MEN1NPC1RAB9A | |
| Pyrazine SCHEMBL27608298 | 0.79 | — | — | |
| Pyrazine SCHEMBL28076131 | 0.79 | — | — | |
| Formic Acid Methyl Ester SCHEMBL28869151 | 0.78 | CYP19A1 (0.39) | GCGRCYP19A1KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102015636-B | Azetidines and cyclobutanes as histamine H3 receptor antagonists | EVOTEC NEUROSCIENCES GMBH | 2014-08-13 | — | — | CN | disclosed |
| CN-101454311-B | Salt of phenoxypyridine derivative, crystal thereof and process for producing the same | EISAI R&D MAN CO LTD | 2013-03-27 | — | — | CN | disclosed |
| CN-102015636-A | Azetidines and cyclobutanes as histamine H3 receptor antagonists | EVOTEC NEUROSCIENCES GMBH | 2011-04-13 | — | — | CN | disclosed |
| CN-1711347-B | Use of metal complex compounds as oxidation catalysts | CIBA SC HOLDING AG | 2010-05-26 | — | — | CN | disclosed |
| CN-101454311-A | Salt of phenoxypyridine derivative, crystal thereof and process for producing the same | EISAI R&D MAN CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-101415493-A | Use of metal complexes as oxidation catalysts | CIBA SC HOLDING AG (CH) | 2009-04-22 | — | — | CN | disclosed |
| CN-101163693-A | Antibacterial piperidine derivatives | ASTRAZENECA AB (SE) | 2008-04-16 | — | — | CN | disclosed |
| CN-101098753-A | Use of metal complexes with bispyridylpyrimidine or bispyridyltriazine ligands as catalysts for reactions with peroxides for bleaching coloured stains on hard surfaces | CIBA SC HOLDING AG (CH) | 2008-01-02 | — | — | CN | disclosed |
| CN-1711347-A | Use of metal complex compounds as oxidation catalysts | CIBA SC HOLDING AG (CH) | 2005-12-21 | — | — | CN | disclosed |