Chlorobenzene

Chlorobenzene

SCHEMBL28088147

CCOC=O.Clc1ccccc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
KDM4E B2RXH2 3/20 0.36
ALDH1A1 P00352 3/20 0.36
HPGD P15428 2/20 0.36
RECQL P46063 2/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
MAPT P10636 2/20 0.36
LMNA P02545 2/20 0.36
ATM Q13315 2/20 0.36
MEN1 O00255 5/20 0.35
KMT2A Q03164 5/20 0.35
AOX1 Q06278 1/20 0.35
HSD17B10 Q99714 2/20 0.35
CASP1 P29466 1/20 0.35
CASP3 P42574 1/20 0.35
CASP7 P55210 1/20 0.35
SENP8 Q96LD8 1/20 0.35
SENP7 Q9BQF6 1/20 0.35
SENP6 Q9GZR1 1/20 0.35
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Dichlorobenzene SCHEMBL27842897 0.89 HSD17B10 (0.42) TSHRKDM4EALDH1A1HPGDRECQL
Chlorobenzene SCHEMBL28303662 0.85 OPRM1 (0.35) TSHRALDH1A1MEN1KMT2AHSD17B10
1,2-Dichlorobenzene SCHEMBL27256387 0.85 LMNA (0.43) TSHRKDM4EALDH1A1HPGDRECQL
Biphenyl SCHEMBL27961596 0.83 ALDH1A1 (0.41) KDM4EALDH1A1HPGDSMN1; SMN2MAPT
Benzene SCHEMBL18406222 0.82 ALDH1A1 (0.32) KDM4EALDH1A1HPGDRECQLMEN1
Ethoxycarbonyl Group SCHEMBL27558742 0.81 DHODH (0.40) KDM4EALDH1A1HPGDSMN1; SMN2MAPT
Toluene SCHEMBL27550219 0.81 TSHR (0.48) TSHRKDM4EALDH1A1HPGDRECQL
Naphthalene SCHEMBL27488215 0.80 ALDH1A1 (0.40) TSHRKDM4EALDH1A1HPGDMAPT
Isopropylbenzene SCHEMBL28470997 0.80 TYR (0.41) ALDH1A1MAPTLMNAMEN1KMT2A
Ethoxycarbonyl Group SCHEMBL28116314 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110003271-A The preparation method of aromatic compound 住友化学株式会社 2019-07-12 CN disclosed
CN-107004768-A Organic semiconductor composition containing a liquid medium 巴斯夫欧洲公司 2017-08-01 CN disclosed
CN-104540871-B The preparation method of aromatic compound 住友化学株式会社 2016-08-24 CN disclosed