Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.47 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27620989 | 0.88 | MCHR1 (0.35) | MCHR1CDK8CDK5ROCK1CLK4 | |
| SCHEMBL27602417 | 0.87 | MCHR1 (0.47) | MCHR1CDK8CDK5ROCK1CLK4 | |
| SCHEMBL27620968 | 0.84 | ALDH1A1 (0.37) | MCHR1CDK8CDK5ROCK1CLK4 | |
| SCHEMBL27602535 | 0.84 | CA1 (0.42) | ALDH1A1TSHRADRA2CADRA2AADRA2B | |
| SCHEMBL27528404 | 0.83 | MCHR1 (0.42) | MCHR1ALDH1A1TSHRSMN1; SMN2ADRB2 | |
| SCHEMBL27602427 | 0.83 | NR2E1 (0.39) | MCHR1ALDH1A1TSHRADRB2ADRB1 | |
| SCHEMBL27602410 | 0.80 | MCHR1 (0.33) | MCHR1CDK8CDK5ROCK1CLK4 | |
| SCHEMBL27602409 | 0.80 | MCHR1 (0.48) | MCHR1ALDH1A1TSHRADRB2ADRB1 | |
| SCHEMBL12666819 | 0.80 | MCHR1 (0.43) | MCHR1CDK8CDK5ROCK1CLK4 | |
| SCHEMBL1395548 | 0.79 | LMNA (0.37) | ALDH1A1TSHRSMN1; SMN2ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1751269-A | Halogenated oxime derivatives and their use as latent acids | CIBA SC HOLDING AG (CH) | 2006-03-22 | — | — | CN | disclosed |
| CN-1628268-A | Sulfonic acid derivatives and their use as latent acids | CIBA SC HOLDING AG (CH) | 2005-06-15 | — | — | CN | disclosed |