Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 4/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 5/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27907749 | 0.75 | GRN (0.46) | GRNSORT1MAPTKMT2AHPGD | |
| SCHEMBL27381532 | 0.70 | F2 (0.42) | ALDH1A1MAPTHSD17B10KMT2ALMNA | |
| SCHEMBL28008522 | 0.69 | TDP1 (0.48) | ALDH1A1MAPTHSD17B10KMT2ALMNA | |
| SCHEMBL13532243 | 0.69 | TP53 (0.48) | GRNSORT1ALDH1A1MAPTHPGD | |
| SCHEMBL1409505 | 0.69 | PTGS1 (0.57) | GRNSORT1ALDH1A1HPGDTDP1 | |
| SCHEMBL2082052 | 0.69 | GRN (0.55) | GRNSORT1ALDH1A1MAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL3173855 | 0.68 | TP53 (0.47) | GRNSORT1ALDH1A1MAPTHPGD | |
| SCHEMBL20603916 | 0.67 | GRN (0.47) | GRNSORT1MAPK13MAPK12MAPK11 | |
| SCHEMBL2084183 | 0.67 | GRN (0.49) | GRNSORT1ALDH1A1MAPK13MAPK12 | |
| SCHEMBL1264553 | 0.66 | CYP1A2 (0.61) | GRNSORT1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102341384-B | P38 map kinase inhibitors | RESPIVERT LTD | 2014-11-12 | — | — | CN | disclosed |
| CN-102341384-A | P38 map kinase inhibitors | RESPIVERT LTD | 2012-02-01 | — | — | CN | disclosed |
| CN-1756849-A | Modulation of protein functionality | DECIPHERA PHARMACEUTICALS LLC (US) | 2006-04-05 | — | — | CN | disclosed |