Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 4/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.46 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KLK3 | P07288 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20603916 | 0.80 | GRN (0.47) | GRNSORT1KDM4EMAPK13MAPK12 | |
| SCHEMBL4139015 | 0.77 | KDM4E (0.44) | GRNSORT1MAP3K14KDM4EMAPK13 | |
| SCHEMBL27621809 | 0.75 | GRN (0.43) | GRNSORT1MAPTKMT2AKDM4E | |
| SCHEMBL2551230 | 0.75 | KLK3 (0.52) | MAP3K14MAPTKMT2AKLK3ELANE | |
| SCHEMBL6054028 | 0.74 | ENPP3 (0.43) | GRNSORT1ELANEKDM4ESMN1; SMN2 | |
| SCHEMBL667656 | 0.72 | KDM4E (0.40) | GRNSORT1MAPTKMT2AELANE | |
| SCHEMBL14378912 | 0.72 | KDM4E (0.40) | GRNSORT1KDM4ENPC1MAPK13 | |
| SCHEMBL2082052 | 0.71 | GRN (0.55) | GRNSORT1MAPTKMT2AMEN1 | |
| SCHEMBL15046195 | 0.70 | KDM4E (0.44) | GRNSORT1KDM4E | |
| SCHEMBL13265589 | 0.70 | KDM4E (0.44) | GRNSORT1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103131206-A | Pyrazolopyridine benzocoumarin dye derivative and synthesis method and application thereof | CHINESE ACAD TECH INST PHYSICS | 2013-06-05 | — | — | CN | disclosed |