Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL103217 | 0.87 | PARP1 (0.46) | PARP1USP2SMN1; SMN2SETD7HPGD | |
| SCHEMBL102292 | 0.87 | PARP1 (0.46) | PARP1USP2SMN1; SMN2SETD7HPGD | |
| SCHEMBL102293 | 0.87 | PARP1 (0.46) | PARP1USP2SMN1; SMN2SETD7HPGD | |
| Piperazine SCHEMBL28853588 | 0.85 | NR1H2 (0.45) | NR1H2USP2SMN1; SMN2MAPK1MEN1 | |
| Potassium SCHEMBL30616188 | 0.85 | PARP1 (0.45) | PARP1USP2SMN1; SMN2SETD7HPGD | |
| Methane SCHEMBL28975622 | 0.85 | PARP1 (0.45) | PARP1USP2SMN1; SMN2SETD7HPGD | |
| Hydrochloric Acid SCHEMBL377440 | 0.85 | PARP1 (0.45) | PARP1USP2SMN1; SMN2SETD7HPGD | |
| SCHEMBL105348 | 0.85 | NR1H2 (0.47) | NR1H2USP2SMN1; SMN2MAPK1MEN1 | |
| SCHEMBL16843 | 0.85 | NR1H2 (0.47) | NR1H2USP2SMN1; SMN2MAPK1MEN1 | |
| SCHEMBL16018 | 0.85 | NR1H2 (0.47) | NR1H2USP2SMN1; SMN2MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100360510-C | Process for producing oxycarbonyl-substituted piperazine derivative | TORAY FINECHEMICALS CO LTD (JP) | 2008-01-09 | — | — | CN | disclosed |
| CN-1681797-A | Process for producing oxycarbonyl-substituted piperazine derivative | TORAY FINECHEMICALS CO LTD (JP) | 2005-10-12 | — | — | CN | disclosed |