Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL1071783 | 1.00 | DAO (0.42) | DAOTSHRNAPRTALDH1A1RAB9A | |
| Benzoic Acid SCHEMBL9856616 | 0.89 | TSHR (0.47) | DAOTSHRNAPRTALDH1A1RAB9A | |
| Benzoic Acid SCHEMBL1334580 | 0.89 | TSHR (0.47) | DAOTSHRNAPRTALDH1A1RAB9A | |
| Benzoic Acid SCHEMBL28760458 | 0.88 | DAO (0.40) | DAOTSHRNAPRTALDH1A1RAB9A | |
| Benzoic Acid SCHEMBL1071207 | 0.86 | TSHR (0.44) | DAOTSHRNAPRTALDH1A1RAB9A | |
| Benzoic Acid SCHEMBL1070315 | 0.86 | DAO (0.44) | DAOTSHRNAPRTALDH1A1RAB9A | |
| Benzoic Acid SCHEMBL28354560 | 0.85 | DAO (0.42) | DAOTSHRNAPRTALDH1A1RAB9A | |
| Benzoic Acid SCHEMBL1784830 | 0.84 | TSHR (0.48) | DAOTSHRNAPRTALDH1A1RAB9A | |
| Benzoic Acid SCHEMBL1783591 | 0.82 | DAO (0.40) | DAOTSHRNAPRTALDH1A1RAB9A | |
| Benzoic Acid SCHEMBL1785118 | 0.81 | DAO (0.39) | DAOTSHRNAPRTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1743346-A | Catalyst component for olefinic polymerization and its catalyst | CHINA PETROCHEMICAL CORP (CN) | 2006-03-08 | — | — | CN | disclosed |
| CN-1743348-A | Catalyst component for olefinic polymerization and its catalyst | CHINA PETROCHEMICAL CORP (CN) | 2006-03-08 | — | — | CN | disclosed |