Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL9856616 | 0.95 | TSHR (0.47) | DAOTSHRNAPRTALDH1A1RAB9A | |
| Benzoic Acid SCHEMBL1334580 | 0.95 | TSHR (0.47) | DAOTSHRNAPRTALDH1A1RAB9A | |
| Benzoic Acid SCHEMBL27622992 | 0.85 | DAO (0.42) | DAOTSHRNAPRTALDH1A1RAB9A | |
| Benzoic Acid SCHEMBL1071783 | 0.85 | DAO (0.42) | DAOTSHRNAPRTALDH1A1RAB9A | |
| SCHEMBL1275819 | 0.83 | TP53 (0.36) | TSHRALDH1A1 | |
| SCHEMBL167278 | 0.83 | TP53 (0.36) | TSHRALDH1A1 | |
| Benzoic Acid SCHEMBL28689306 | 0.83 | DAO (0.44) | DAOTSHRNAPRTALDH1A1RAB9A | |
| Benzoic Acid SCHEMBL1070315 | 0.83 | DAO (0.44) | DAOTSHRNAPRTALDH1A1RAB9A | |
| Benzoic Acid SCHEMBL29197419 | 0.83 | TRPA1 (0.46) | TSHRALDH1A1RAB9ATRPA1CYP1A2 | |
| Benzoic Acid SCHEMBL28685385 | 0.80 | TSHR (0.52) | DAOTSHRNAPRTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117500661-A | Laminated glazing with improved sound-insulating properties | 首诺公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-115103867-B | Polyurethane-based thermal interface materials comprising silane-terminated urethane prepolymers | DDP特种电子材料美国有限责任公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-116917121-A | Poly (vinyl butyral) composition for use with solar energy additives | 首诺公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-116669923-A | Method for recovering poly (vinyl butyral) from a multi-layer poly (vinyl butyral) sheet | 首诺公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-116018545-A | Head-up display system with half-wave plate optimized for better performance | 伊士曼化工公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-111741984-B | Vinyl chloride resin aggregate particles, method for producing same, composition for metal can coating, composition for marking film, and coating film | 株式会社钟化 | 2022-12-27 | — | — | CN | disclosed |
| CN-115103867-A | Polyurethane-based thermal interface materials comprising silane-terminated urethane prepolymers | DDP特种电子材料美国有限责任公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-114901472-A | Interlayers having improved graded bands | 首诺公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-114845859-A | Wedge-shaped multilayer interlayer with varying thickness outer skin | 首诺公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-110087876-B | Asymmetric laminates including asymmetric multilayer interlayers | 首诺公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-107000383-B | Multiple layer interlayers of polyvinyl acetal and cellulose ester | 首诺公司 | 2020-06-16 | — | — | CN | disclosed |
| CN-111263738-A | Laminated glass | ＡＧＣ株式会社 | 2020-06-09 | — | — | CN | disclosed |
| CN-111201134-A | Poly (vinyl acetal) resin compositions, layers and interlayers having enhanced properties | 首诺公司 | 2020-05-26 | — | — | CN | disclosed |
| CN-111201136-A | Poly (vinyl acetal) resin compositions, layers and interlayers having enhanced properties | 首诺公司 | 2020-05-26 | — | — | CN | disclosed |
| CN-111201135-A | Poly (vinyl acetal) resin compositions, layers and interlayers having enhanced properties | 首诺公司 | 2020-05-26 | — | — | CN | disclosed |
| CN-111093981-A | Laminated glass and interlayers comprising cellulose ester | 首诺公司 | 2020-05-01 | — | — | CN | disclosed |
| CN-107000386-B | Poly (vinyl acetal) resin compositions, layers and interlayers having enhanced optical properties | 首诺公司 | 2020-03-06 | — | — | CN | disclosed |
| CN-107148447-B | Polymer interlayers comprising compatibilizers | 首诺公司 | 2020-02-21 | — | — | CN | disclosed |
| CN-107000413-B | Polymer interlayers having improved acoustical properties | 首诺公司 | 2020-02-14 | — | — | CN | disclosed |
| CN-107000414-B | Poly (vinyl acetal) resin compositions, layers and interlayers having enhanced optical properties | 首诺公司 | 2020-02-14 | — | — | CN | disclosed |