Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL9856616 | 1.00 | TSHR (0.47) | TSHRDAONAPRTALDH1A1RAB9A | |
| Benzoic Acid SCHEMBL28354560 | 0.95 | DAO (0.42) | TSHRDAONAPRTALDH1A1RAB9A | |
| Benzoic Acid SCHEMBL1071783 | 0.89 | DAO (0.42) | TSHRDAONAPRTALDH1A1RAB9A | |
| Benzoic Acid SCHEMBL27622992 | 0.89 | DAO (0.42) | TSHRDAONAPRTALDH1A1RAB9A | |
| Benzoic Acid SCHEMBL28689306 | 0.87 | DAO (0.44) | TSHRDAONAPRTALDH1A1RAB9A | |
| Benzoic Acid SCHEMBL1070315 | 0.87 | DAO (0.44) | TSHRDAONAPRTALDH1A1RAB9A | |
| Benzoic Acid SCHEMBL29197419 | 0.87 | TRPA1 (0.46) | TSHRALDH1A1RAB9ATRPA1CYP1A2 | |
| Benzoic Acid SCHEMBL28685385 | 0.84 | TSHR (0.52) | TSHRDAONAPRTALDH1A1RAB9A | |
| Benzoic Acid SCHEMBL1784503 | 0.83 | TSHR (0.50) | TSHRDAONAPRTALDH1A1RAB9A | |
| Benzoic Acid SCHEMBL1786487 | 0.82 | TSHR (0.54) | TSHRDAONAPRTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290623-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118290625-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118290624-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-117756970-A | Catalyst for butene-1 polymerization and application thereof | 中国石油化工股份有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-115850892-A | Intermediate film and laminated glass comprising same | 长春石油化学股份有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-114008119-A | Glycol ether aryl ester plasticizers | 伊士曼化工公司 | 2022-02-01 | — | — | CN | claimed |
| CN-113444189-A | Catalyst for olefin polymerization and application thereof | 中国石油化工股份有限公司 | 2021-09-28 | — | — | CN | claimed |
| CN-109071885-B | Latex composition for dip molding, and molded article prepared therefrom | 株式会社LG化学 | 2021-08-17 | — | — | CN | claimed |
| CN-112292742-A | Low tortuosity electrodes and electrolytes and methods of making the same | 菲斯克股份有限公司 | 2021-01-29 | — | — | CN | claimed |
| CN-111907155-A | Intermediate film and laminated glass comprising same | 长春石油化学股份有限公司 | 2020-11-10 | — | — | CN | claimed |
| EP-1862225-B1 | Pencil with a sharpenable wrapping and a gripping area on the surface of the pencil | FABER CASTELL AG (DE) | 2013-07-10 | — | — | EP | claimed |
| US-20130137789-A1 | POLYVINYL CHLORIDE COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 2013-05-30 | — | — | US | claimed |
| US-8372912-B2 | Polyvinyl chloride compositions | EASTMAN CHEMICAL COMPANY (US) | 2013-02-12 | — | — | US | claimed |
| EP-1913069-A1 | POLYVINYL CHLORIDE COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 2008-04-23 | — | — | EP | claimed |
| WO-2007021987-A1 | POLYVINYL CHLORIDE COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 2007-02-22 | — | — | WO | claimed |
| US-20070037926-A1 | Polyvinyl chloride compositions | EASTMAN CHEMICAL COMPANY | 2007-02-15 | — | — | US | claimed |
| EP-0416822-A2 | Stain-resistant plasticizer compositions and method of making same | VELSICOL CHEMICAL CORPORATION (US) | 1991-03-13 | — | — | EP | claimed |
| CN-118290624-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| US-20030035917-A1 | Image making medium | HYMAN SYDNEY (US) | 2003-02-20 | — | — | US | disclosed |
| EP-0416822-A2 | Stain-resistant plasticizer compositions and method of making same | VELSICOL CHEMICAL CORPORATION (US) | 1991-03-13 | — | — | EP | disclosed |