Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfanilamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 15/20 | 0.74 |
| ▸ | CA9 | Q16790 | 14/20 | 0.74 |
| ▸ | CA1 | P00915 | 13/20 | 0.74 |
| ▸ | CA12 | O43570 | 12/20 | 0.74 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.74 |
| ▸ | CA7 | P43166 | 5/20 | 0.74 |
| ▸ | CA6 | P23280 | 3/20 | 0.74 |
| ▸ | CA5A | P35218 | 3/20 | 0.74 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.74 |
| ▸ | TSHR | P16473 | 3/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.74 |
| ▸ | USP2 | O75604 | 1/20 | 0.74 |
| ▸ | CA4 | P22748 | 1/20 | 0.74 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.74 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | CA3 | P07451 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | DHFR | P00374 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfanilamide SCHEMBL28520704 | 0.91 | CA2 (0.74) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL9017524 | 0.89 | CA2 (0.71) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL28461277 | 0.89 | CA2 (0.71) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL20567505 | 0.89 | CA2 (0.77) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL28201481 | 0.89 | CA2 (0.85) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL28083764 | 0.88 | CA2 (0.63) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL28279833 | 0.88 | CA2 (0.68) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL28616095 | 0.86 | CA2 (0.90) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL8449748 | 0.86 | CA2 (0.90) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL4188099 | 0.86 | CA2 (0.90) | CA2CA9CA1CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114599386-A | Compositions and synergistic methods for treating infections | 生物保护医疗公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-107708675-A | The composition and kit of pseudoplastic behavior microgel matrix | 罗查尔工业有限责任公司 | 2018-02-16 | — | — | CN | disclosed |
| CN-102939097-B | Novel synergistic pharmaceutical composition for topical application | BHARAT BIOTECH INTERNATIONAL LTD. (IN) | 2016-05-11 | — | — | CN | disclosed |
| CN-103735911-B | A kind of medicine and preparation method who treats rubella | LU BINGFANG (CN) | 2016-05-04 | — | — | CN | disclosed |
| CN-104784415-A | Traditional Chinese medicine pill for treating acute eruptive infectious disease and preparation method | ZHANG YAN | 2015-07-22 | — | — | CN | disclosed |
| CN-103735911-A | Medicine for treating rubella and preparation method thereof | LU BINGFANG | 2014-04-23 | — | — | CN | disclosed |
| CN-1678188-B | Nucleic acid compositions for modulating immune responses | COLEY PHARM GROUP INC | 2012-10-10 | — | — | CN | disclosed |
| CN-1678188-A | Nucleic acid compositions for modulating immune responses | COLEY PHARM GROUP INC (US) | 2005-10-05 | — | — | CN | disclosed |