Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfanilamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 16/20 | 0.90 |
| ▸ | CA9 | Q16790 | 14/20 | 0.90 |
| ▸ | CA1 | P00915 | 13/20 | 0.90 |
| ▸ | CA12 | O43570 | 12/20 | 0.90 |
| ▸ | CA7 | P43166 | 6/20 | 0.90 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.90 |
| ▸ | CA5A | P35218 | 5/20 | 0.90 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.90 |
| ▸ | CA6 | P23280 | 4/20 | 0.90 |
| ▸ | TSHR | P16473 | 3/20 | 0.90 |
| ▸ | CA4 | P22748 | 3/20 | 0.90 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.90 |
| ▸ | USP2 | O75604 | 1/20 | 0.90 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.90 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.90 |
| ▸ | CA3 | P07451 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MPO | P05164 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfanilamide SCHEMBL30659052 | 0.95 | CA2 (1.00) | CA2CA9CA1CA12CA7 | |
| Sulfanilamide SCHEMBL740 | 0.95 | CA2 (1.00) | CA2CA9CA1CA12CA7 | |
| Sulfanilamide SCHEMBL31544839 | 0.95 | CA2 (1.00) | CA2CA9CA1CA12CA7 | |
| Sulfanilamide SCHEMBL2798899 | 0.95 | CA2 (1.00) | CA2CA9CA1CA12CA7 | |
| Sulfanilamide SCHEMBL27364276 | 0.92 | CA2 (0.85) | CA2CA9CA1CA12CA7 | |
| Sulfanilamide SCHEMBL28201481 | 0.92 | CA2 (0.85) | CA2CA9CA1CA12CA7 | |
| Sulfanilamide SCHEMBL3273308 | 0.92 | CA2 (0.94) | CA2CA9CA1CA12CA7 | |
| Sulfanilamide SCHEMBL5894222 | 0.92 | CA2 (0.94) | CA2CA9CA1CA12CA7 | |
| Sulfanilamide SCHEMBL8030126 | 0.92 | CA2 (0.94) | CA2CA9CA1CA12CA7 | |
| Sulfanilamide SCHEMBL22501553 | 0.92 | CA2 (0.94) | CA2CA9CA1CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109251588-A | Inorganic nano material ink and its preparation method and application, QLED device | TCL集团股份有限公司 | 2019-01-22 | — | — | CN | claimed |
| CN-104918945-B | Tricyclic fused thiophene derivatives as JAK inhibitors | 因赛特公司 | 2018-01-05 | — | — | CN | claimed |
| EP-3247703-A1 | IMPROVED PROCESS FOR PREPARING STATIN PRECURSOR | DSM Sinochem Pharmaceuticals Netherlands B.V. (NL) | 2017-11-29 | — | — | EP | claimed |
| WO-2016151104-A1 | IMPROVED PROCESS FOR PREPARING A STATIN PRECURSOR | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2016-09-29 | — | — | WO | claimed |
| WO-2016116589-A1 | IMPROVED PROCESS FOR PREPARING STATIN PRECURSOR | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2016-07-28 | — | — | WO | claimed |
| EP-4313969-A1 | N2-PHENYLPYRIMIDINE-2,4-DIAMINE COMPOUNDS, AND PREPARATION METHODS AND METHODS OF USE THEREOF | Bridge Biotherapeutics, Inc. (KR) | 2024-02-07 | — | — | EP | disclosed |
| EP-4034107-A1 | JAK INHIBITORS | Vimalan Biosciences, Inc. (US) | 2022-08-03 | — | — | EP | disclosed |
| EP-3898637-A1 | RAPAMYCIN DERIVATIVES | Novartis AG (CH) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020128861-A1 | RAPAMYCIN DERIVATIVES | NOVARTIS AG (CH) | 2020-06-25 | — | — | WO | disclosed |
| CN-110520409-A | Compounds and compositions for intracellular delivery of therapeutic agents | MODERNATX INC | 2019-11-29 | — | — | CN | disclosed |
| CN-110483423-A | P2X4 receptor antagonist | NIPPON CHEMIPHAR CO | 2019-11-22 | — | — | CN | disclosed |
| CN-105934246-B | Tetrahydroquinoline compositions as BET bromodomain inhibitors | 福马疗法公司 | 2019-10-22 | — | — | CN | disclosed |
| CN-104321320-B | Prepare statin facilitates method | 意大利合成制造有限公司 | 2017-05-31 | — | — | CN | disclosed |
| US-20170071946-A1 | PYRAZOLOPYRIDINES AND PYRAZOLOPYRIMIDINES | PFIZER INC. (US) | 2017-03-16 | — | — | US | disclosed |
| US-9518052-B2 | Pyrazolopyridines and pyrazolopyrimidines | PFIZER INC. (US) | 2016-12-13 | — | — | US | disclosed |
| WO-2016151104-A1 | IMPROVED PROCESS FOR PREPARING A STATIN PRECURSOR | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2016-09-29 | — | — | WO | disclosed |
| WO-2016125086-A1 | PROCESSES FOR THE PREPARATION OF ROSUVASTATIN OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | LAURUS LABS PRIVATE LIMITED (IN) | 2016-08-11 | — | — | WO | disclosed |
| WO-2016116589-A1 | IMPROVED PROCESS FOR PREPARING STATIN PRECURSOR | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2016-07-28 | — | — | WO | disclosed |
| US-20150329542-A1 | PYRAZOLOPYRIDINES AND PYRAZOLOPYRIMIDINES | PFIZER INC. | 2015-11-19 | — | — | US | disclosed |
| US-20090069320-A1 | Substituted 4-Amino-Quinazoline Compounds with Metabotropic Glutamate Receptor Regulating Activity and Uses Thereof | GRUENENTHAL GMBH (DE) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150329542-A1 | PYRAZOLOPYRIDINES AND PYRAZOLOPYRIMIDINES | HRH2, HRH4, HRH1 | CA2 361/4885CA9 1782/4885CA1 2724/4885 |
| US-20090069320-A1 | Substituted 4-Amino-Quinazoline Compounds with Metabotropic Glutamate Receptor Regulating Activity and Uses Thereof | GRM1, GRIN1, GRM2 | CA2 1136/4885CA9 4317/4885CA1 1637/4885 |
| US-20170071946-A1 | PYRAZOLOPYRIDINES AND PYRAZOLOPYRIMIDINES | HRH2, HRH4, HRH1 | CA2 361/4885CA9 1782/4885CA1 2724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.