Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20424197 | 0.84 | LMNA (0.62) | ALDH1A1LMNAGAATSHRMAPT | |
| SCHEMBL25235299 | 0.83 | GAA (0.51) | ALDH1A1LMNAGAANPSR1MAPT | |
| SCHEMBL27642525 | 0.82 | SMN1; SMN2 (0.59) | ALDH1A1LMNAGAANPSR1TSHR | |
| SCHEMBL22106068 | 0.82 | GAA (0.44) | ALDH1A1LMNAGAANPSR1TSHR | |
| SCHEMBL22106070 | 0.81 | GAA (0.43) | ALDH1A1LMNAGAANPSR1TSHR | |
| SCHEMBL3191411 | 0.80 | ALDH1A1 (0.63) | ALDH1A1LMNATSHRMAPTTP53 | |
| SCHEMBL5361832 | 0.80 | GAA (0.56) | ALDH1A1GAANPSR1MAPTMAPK1 | |
| SCHEMBL1250641 | 0.80 | GAA (0.53) | ALDH1A1LMNAGAANPSR1MAPT | |
| SCHEMBL21225478 | 0.79 | ALDH1A1 (0.54) | ALDH1A1LMNAGAANPSR1TSHR | |
| SCHEMBL7038455 | 0.79 | GAA (0.56) | ALDH1A1LMNAGAANPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100418944-C | Amino alcohol derivatives, pharmaceutical compositions containing the same, and use thereof | KISSEI PHARMACEUTICAL (JP) | 2008-09-17 | — | — | CN | disclosed |
| CN-1751019-A | Amino alcohol derivatives, pharmaceutical compositions containing the same, and use thereof | KISSEI PHARMACEUTICAL (JP) | 2006-03-22 | — | — | CN | disclosed |