SCHEMBL27624328

SCHEMBL27624328

[CH2]C(O)C1CCc2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.43
PDPK1 O15530 1/20 0.43
CYP11B2 P19099 1/20 0.41
CHRNA7 P36544 1/20 0.40
SIGMAR1 Q99720 3/20 0.39
PIN1 Q13526 1/20 0.39
ACP3 P15309 1/20 0.39
HTR1A P08908 2/20 0.39
SLC18A3 Q16572 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19838830 0.81 PDPK1 (0.47) IDO1PDPK1CYP11B2SIGMAR1
SCHEMBL9499564 0.81 IDO1 (0.47) IDO1PDPK1CYP11B2
SCHEMBL7678037 0.78 PDPK1 (0.44) IDO1PDPK1CYP11B2SIGMAR1PIN1
SCHEMBL6277434 0.78 HTR1A (0.41) IDO1PDPK1CYP11B2SIGMAR1HTR1A
Methyl Alcohol SCHEMBL14815578 0.77 PRCP (0.49) IDO1PDPK1CYP11B2SIGMAR1
SCHEMBL7407546 0.77 IDO1 (0.40) IDO1PDPK1CYP11B2CHRNA7SIGMAR1
SCHEMBL11364491 0.77 HTR1A (0.43) IDO1PDPK1SIGMAR1HTR1A
SCHEMBL30298337 0.76 PRCP (0.52) IDO1PDPK1CYP11B2SIGMAR1
SCHEMBL30298334 0.76 PRCP (0.52) IDO1PDPK1CYP11B2SIGMAR1
SCHEMBL7117304 0.76 IDO1 (0.50) IDO1PDPK1CYP11B2CHRNA7SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102066554-A Cell adhesion promoting agent and method of promoting cell adhesion UNIV KYOTO 2011-05-18 CN disclosed
CN-100543022-C 2-furancarboxylic acid hydrazide compound and contain the pharmaceutical composition of this compound DAINIPPON PHARMACEUTICAL CO (JP) 2009-09-23 CN disclosed
CN-1628111-A 2-furancarboxylic acid hydrazides and pharmaceutical compositions containing the same DAINIPPON PHARMACEUTICAL CO (JP) 2005-06-15 CN disclosed