Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.61 |
| ▸ | DDT | P30046 | 1/20 | 0.48 |
| ▸ | CCR1 | P32246 | 13/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27643790 | 0.94 | ELANE (0.64) | ELANEDDTCCR1 | |
| SCHEMBL5757082 | 0.91 | ELANE (0.63) | ELANEDDTCCR1EPHX2 | |
| SCHEMBL5757939 | 0.91 | ELANE (0.65) | ELANEDDTCCR1EPHX2KDM4E | |
| SCHEMBL5756300 | 0.89 | ELANE (0.63) | ELANEDDTCCR1 | |
| SCHEMBL5757244 | 0.85 | ELANE (0.67) | ELANEDDTCCR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5757669 | 0.84 | ELANE (0.65) | ELANEDDTCCR1ALDH1A1 | |
| SCHEMBL5755788 | 0.82 | ELANE (0.79) | ELANEDDTCCR1KDM4EALDH1A1 | |
| SCHEMBL5759185 | 0.81 | ELANE (0.68) | ELANEDDTCCR1KDM4EALDH1A1 | |
| SCHEMBL5758687 | 0.81 | ELANE (0.73) | ELANEDDTCCR1KDM4EALDH1A1 | |
| SCHEMBL5760891 | 0.80 | ELANE (0.75) | ELANEDDTCCR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1711243-A | 2-pyridone derivatives as inhibitors of neutrophil elastase | ASTRAZENECA AB (SE) | 2005-12-21 | — | — | CN | disclosed |