Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 8/20 | 0.51 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.49 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.49 |
| ▸ | GRPR | P30550 | 4/20 | 0.46 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18402423 | 0.92 | REN (0.60) | RENERAP2ERAP1LNPEPGRPR | |
| SCHEMBL12374166 | 0.90 | REN (0.54) | RENERAP2ERAP1LNPEPGRPR | |
| SCHEMBL27624690 | 0.90 | SLC15A2 (0.57) | RENERAP2ERAP1LNPEPGRPR | |
| SCHEMBL16350346 | 0.90 | REN (0.49) | RENERAP2ERAP1LNPEPGRPR | |
| SCHEMBL12972224 | 0.90 | REN (0.49) | RENERAP2ERAP1LNPEPGRPR | |
| SCHEMBL12232397 | 0.89 | REN (0.48) | RENERAP2ERAP1LNPEPGRPR | |
| SCHEMBL27644992 | 0.87 | GRPR (0.53) | RENGRPR | |
| SCHEMBL16317506 | 0.86 | REN (0.51) | RENGRPR | |
| SCHEMBL13781414 | 0.84 | GRPR (0.57) | GRPR | |
| SCHEMBL18862042 | 0.83 | REN (0.56) | RENERAP2ERAP1LNPEPSLC15A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1897980-A | Improved gastrin releasing peptide compounds | BRACCO IMAGING SPA (IT) | 2007-01-17 | — | — | CN | disclosed |
| CN-1738650-A | Improved gastrin releasing peptide compounds | BRACCO IMAGING SPA (IT) | 2006-02-22 | — | — | CN | disclosed |