SCHEMBL12374166

SCHEMBL12374166

CCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O

nearest known ligand 0.54

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 10/20 0.54
▸ GRPR P30550 6/20 0.48
▸ SLC15A2 Q16348 1/20 0.48
▸ ERAP2 Q6P179 1/20 0.46
▸ ERAP1 Q9NZ08 1/20 0.46
▸ LNPEP Q9UIQ6 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27624690 0.93 SLC15A2 (0.57) RENGRPRSLC15A2ERAP2ERAP1
SCHEMBL27624718 0.90 REN (0.51) RENGRPRSLC15A2ERAP2ERAP1
SCHEMBL18402423 0.90 REN (0.60) RENGRPRSLC15A2ERAP2ERAP1
SCHEMBL16317506 0.88 REN (0.51) RENGRPR
SCHEMBL12972224 0.88 REN (0.49) RENGRPRSLC15A2ERAP2ERAP1
SCHEMBL16350346 0.88 REN (0.49) RENGRPRSLC15A2ERAP2ERAP1
SCHEMBL12972227 0.88 REN (0.53) RENSLC15A2ERAP2ERAP1LNPEP
SCHEMBL27644992 0.87 GRPR (0.53) RENGRPR
SCHEMBL12232397 0.87 REN (0.48) RENGRPRSLC15A2ERAP2ERAP1
SCHEMBL13781414 0.85 GRPR (0.57) GRPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110206606-A1 STABLE RADIOPHARMACEUTICAL COMPOSITIONS AND METHODS FOR PREPARATION BRACCO IMAGING S.P.A. (IT) 2011-08-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110206606-A1 STABLE RADIOPHARMACEUTICAL COMPOSITIONS AND METHODS FOR PREPARATION GRPR, GIPR, SSTR3 REN 865/4885GRPR 1/4885SLC15A2 2495/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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