Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2764270 | 0.95 | THRA (0.40) | HDAC3HDAC1HDAC2NPC1RAB9A | |
| SCHEMBL270602 | 0.90 | TP53 (0.47) | KDM4E | |
| SCHEMBL29663544 | 0.90 | TP53 (0.47) | KDM4E | |
| SCHEMBL19856519 | 0.85 | SMN1; SMN2 (0.43) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL690293 | 0.84 | ALDH1A1 (0.44) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL29716211 | 0.83 | CYP2D6 (0.49) | LMNAALDH1A1CES2CES1 | |
| SCHEMBL10004451 | 0.81 | TSHR (0.46) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL19856520 | 0.80 | PLA2G4B (0.44) | NPC1RAB9A | |
| SCHEMBL690294 | 0.79 | TP53 (0.49) | ALDH1A1 | |
| SCHEMBL313672 | 0.79 | TSHR (0.54) | LMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108429-B | Compound (I) | 联邦科学与工业研究组织 | 2022-08-19 | — | — | CN | disclosed |
| CN-109310620-B | Hair care composition | 西姆莱斯股份公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-105380810-B | Stabilization of cosmetic compositions | 巴斯夫欧洲公司 | 2021-02-26 | — | — | CN | disclosed |
| CN-111918637-A | Retinol substitute in skin treatment | 西姆莱斯有限公司 | 2020-11-10 | — | — | CN | disclosed |
| CN-102245635-B | Modified variant BOWMAN BIRK protease inhibitors | 丹尼斯科美国公司 | 2016-08-31 | — | — | CN | disclosed |
| CN-104284652-A | Easily formulated zinc oxide powder | BASF SE | 2015-01-14 | — | — | CN | disclosed |
| CN-101360764-B | Preparation of functionalized cationic polymers and their preparation and application in personal care | CIBA HOLDING INC. (CH) | 2011-12-14 | — | — | CN | disclosed |
| CN-102245635-A | Modified variant bowman birk protease inhibitors | DANISCO US INC GENENCOR DIV | 2011-11-16 | — | — | CN | disclosed |
| CN-101155842-B | Cationic polymers as thickeners for aqueous and alcoholic compositions | BASF AG | 2011-08-03 | — | — | CN | disclosed |
| CN-101360764-A | Preparation of functionalized cationic polymers and their preparation and application in personal care | CIBA HOLDING INC (CH) | 2009-02-04 | — | — | CN | disclosed |
| CN-101155842-A | Cationic polymers as thickeners for aqueous and alcoholic compositions | BASF AG (DE) | 2008-04-02 | — | — | CN | disclosed |
| CN-101137724-A | Metal oxide nanoparticles coated with specific n-acylaminomethylene phosphonates | CIBA SC HOLDING AG (CH) | 2008-03-05 | — | — | CN | disclosed |
| CN-1738592-A | Triazine derivatives as UV absorbers | CIBA SC HOLDING AG (CH) | 2006-02-22 | — | — | CN | disclosed |