Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 6/20 | 0.72 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.70 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | POLR1A | O95602 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ECE1 | P42892 | 1/20 | 0.51 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.51 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.51 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27874410 | 0.87 | RAD52 (0.74) | RAD52UHRF1AOX1HTTALDH1A1 | |
| SCHEMBL29369424 | 0.81 | AOX1 (0.78) | RAD52UHRF1AOX1HTTALDH1A1 | |
| SCHEMBL105276 | 0.81 | AOX1 (0.78) | RAD52UHRF1AOX1HTTALDH1A1 | |
| SCHEMBL634175 | 0.80 | RAD52 (0.64) | RAD52UHRF1AOX1HTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL29608361 | 0.80 | AOX1 (0.77) | RAD52UHRF1AOX1HTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL4888175 | 0.80 | AOX1 (0.77) | RAD52UHRF1AOX1HTTALDH1A1 | |
| SCHEMBL635319 | 0.79 | RAD52 (0.63) | RAD52UHRF1AOX1HTTALDH1A1 | |
| SCHEMBL7508011 | 0.79 | RAD52 (0.58) | RAD52UHRF1AOX1HTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL5953779 | 0.79 | AOX1 (0.75) | RAD52UHRF1AOX1HTTALDH1A1 | |
| SCHEMBL10525047 | 0.78 | RAD52 (0.69) | RAD52UHRF1AOX1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1736486-A | Anticancer implantation agent | KONG QINGZHONG (CN) | 2006-02-22 | — | — | CN | claimed |
| CN-1679952-A | Anticarcinogenic medicine composition | LANJIN BIOLOG ENGINEERING CO L (CN) | 2005-10-12 | — | — | CN | claimed |
| CN-104788562-B | Endothelial factor antibody | 特雷康制药公司 | 2019-06-28 | — | — | CN | disclosed |
| CN-103694258-B | For suppressing 1,3,4-thiadiazoles derivative of the spiral shell condensation of KSP kinesin activity | SCHERING CORPORATION (US) | 2016-01-13 | — | — | CN | disclosed |
| CN-102391222-B | As the hydroxamic acid ester of therapeutical agent | PHARMACYCLICS INC. (US) | 2015-10-21 | — | — | CN | disclosed |
| CN-102711809-B | Use anti-endoglin antibody and anti-VEGF agent therapeutic alliance cancer | TRACON PHARMACEUTICALS, INC. (US) | 2015-09-30 | — | — | CN | disclosed |
| CN-104788562-A | Endoglin antibodies | TRACON PHARMACEUTICALS INC | 2015-07-22 | — | — | CN | disclosed |
| CN-102762227-B | Endothelin antibodies | TRACON PHARMACEUTICALS INC | 2015-04-22 | — | — | CN | disclosed |
| CN-103694258-A | Spiro-condensed 1, 3, 4-thiadiazole derivatives for inhibiting ksp kinesin activity | SCHERING CORP | 2014-04-02 | — | — | CN | disclosed |
| CN-101903365-B | Spiro-condensed 1,3, 4-thiadiazole derivatives for inhibiting KSP kinesin activity | MERCK SHARP & DOHME | 2014-02-05 | — | — | CN | disclosed |
| CN-103420988-A | Pyridinone and pyridazinone derivatives as inhibitors of poly(adp-ribose)polymerase (parp) | ANGELETTI P IST RICHERCHE BIO | 2013-12-04 | — | — | CN | disclosed |
| CN-1846679-A | Sustained-release injection containing methotrexate and synergist thereof | JINAN SHUAIHUA MEDICINE SCI TE (CN) | 2006-10-18 | — | — | CN | disclosed |
| CN-1846676-A | Sustained-release injection containing fluorouracil synergist and preparation method thereof | JINAN SHUAIHUA MEDICINE SCI TE (CN) | 2006-10-18 | — | — | CN | disclosed |
| CN-1846674-A | Slow released anticancer injection | JINAN SHUIHUA MEDICINE SCI TEC (CN) | 2006-10-18 | — | — | CN | disclosed |
| CN-1839128-A | Mitotic kinesin inhibitors | MERCK & CO INC (US) | 2006-09-27 | — | — | CN | disclosed |
| CN-1829507-A | Tyrosine kinase inhibitors | MERCK & CO INC (US) | 2006-09-06 | — | — | CN | disclosed |
| CN-1795175-A | Acetylene derivatives as inhibitors of histone deacetylase | AXYS PHARM INC (US) | 2006-06-28 | — | — | CN | disclosed |
| CN-1768031-A | hydroxamates as therapeutic agents | AXYS PHARM INC (US) | 2006-05-03 | — | — | CN | disclosed |
| CN-1736486-A | Anticancer implantation agent | KONG QINGZHONG (CN) | 2006-02-22 | — | — | CN | disclosed |
| CN-1679952-A | Anticarcinogenic medicine composition | LANJIN BIOLOG ENGINEERING CO L (CN) | 2005-10-12 | — | — | CN | disclosed |