Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | GRM8 | O00222 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24288140 | 0.80 | KMO (0.38) | HDAC1ALOX5APFEN1ADRA2AADRA2C | |
| SCHEMBL25592271 | 0.71 | NSD2 (0.41) | NSD2HDAC1HDAC6HDAC5LOXL2 | |
| SCHEMBL1912409 | 0.69 | PDE3B (0.45) | NSD2LOXL2 | |
| SCHEMBL24459502 | 0.69 | MAOB (0.46) | NSD2HDAC1HDAC6HDAC5LOXL2 | |
| SCHEMBL23564745 | 0.67 | LOXL2 (0.39) | LOXL2 | |
| SCHEMBL716197 | 0.66 | LOXL2 (0.46) | HDAC1HDAC6LOXL2ROCK1 | |
| SCHEMBL29615504 | 0.66 | AKT2 (0.49) | LOXL2USP7AKT2 | |
| SCHEMBL22918661 | 0.66 | AKT2 (0.49) | LOXL2USP7AKT2 | |
| SCHEMBL23967513 | 0.65 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL28956664 | 0.65 | ALOX5AP (0.48) | NSD2GRM2LOXL2ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100357297-C | Pyrimidines, method for the production thereof and use thereof | BASF AG (DE) | 2007-12-26 | — | — | CN | disclosed |
| CN-1747958-A | Pyrimidines, methods for the production thereof, and use thereof | BASF AG (DE) | 2006-03-15 | — | — | CN | disclosed |