Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27687723 | 0.89 | TAAR1 (0.36) | TAAR1TDP1HTR2AHTR2CHTR2B | |
| SCHEMBL28166797 | 0.88 | GNAO1 (0.37) | TAAR1 | |
| SCHEMBL27594590 | 0.86 | GNAO1 (0.40) | TAAR1 | |
| SCHEMBL19812634 | 0.86 | GNAO1 (0.40) | TAAR1 | |
| SCHEMBL28002186 | 0.85 | TDP1 (0.31) | TDP1HTR2AHTR2CHTR2B | |
| SCHEMBL27490674 | 0.81 | CA1 (0.30) | — | |
| SCHEMBL27563028 | 0.81 | TDP1 (0.30) | TDP1 | |
| SCHEMBL28752326 | 0.81 | TDP1 (0.30) | TDP1 | |
| SCHEMBL28368182 | 0.81 | — | — | |
| SCHEMBL27531040 | 0.81 | GBA1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100390149-C | Indazole derivatives | KYOWA HAKKO KOGYO KK (JP) | 2008-05-28 | — | — | CN | disclosed |
| CN-1777590-A | Indazole derivatives | KYOWA HAKKO KOGYO KK (JP) | 2006-05-24 | — | — | CN | disclosed |
| CN-87108000-A | The preparation of the piperazine ketone that N-replaces | — | 1988-08-31 | — | — | CN | disclosed |