Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | CA4 | P22748 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27626232 | 0.81 | TAAR1 (0.35) | — | |
| SCHEMBL28752326 | 0.81 | TDP1 (0.30) | — | |
| SCHEMBL27563028 | 0.81 | TDP1 (0.30) | — | |
| SCHEMBL27687723 | 0.79 | TAAR1 (0.36) | — | |
| SCHEMBL28166804 | 0.77 | ALDH1A1 (0.34) | — | |
| SCHEMBL27531040 | 0.77 | GBA1 (0.34) | — | |
| SCHEMBL28166797 | 0.77 | GNAO1 (0.37) | — | |
| SCHEMBL28002186 | 0.77 | TDP1 (0.31) | — | |
| SCHEMBL19812634 | 0.76 | GNAO1 (0.40) | — | |
| SCHEMBL27658474 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114127062-A | Thiadiazolyl derivatives as inhibitors of DNA polymerase Theta | 伊迪亚生物科学有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-1809557-B | Compound | ASTRAZENECA AB | 2012-07-04 | — | — | CN | disclosed |
| CN-101087794-B | Pharmaceutical compounds | HOFFMANN LA ROCHE | 2011-05-18 | — | — | CN | disclosed |
| CN-101479277-A | Pyrimidine derivatives as PI3K inhibitors | PIRAMED LTD (CH) | 2009-07-08 | — | — | CN | disclosed |
| CN-101087794-A | Pharmaceutical compounds | PIRAMED LTD (GB) | 2007-12-12 | — | — | CN | disclosed |
| CN-1809557-A | Compound | ASTRAZENECA AB (SE) | 2006-07-26 | — | — | CN | disclosed |
| CN-1195340-A | Inhibitors of farnesyl-protein transferase | MERCK & CO INC (US) | 1998-10-07 | — | — | CN | disclosed |