Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.33 |
| ▸ | RARB | P10826 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9272470 | 0.98 | TP53 (0.33) | PLA2G2ATP53TSHRNAAAPLA2G4B | |
| SCHEMBL6802034 | 0.79 | NPC1 (0.31) | TP53 | |
| SCHEMBL27657748 | 0.74 | EPHX1 (0.37) | TSHRNAAACES2 | |
| SCHEMBL7818599 | 0.72 | — | — | |
| SCHEMBL27986241 | 0.72 | TSHR (0.31) | TSHR | |
| SCHEMBL4182082 | 0.71 | CHRM2 (0.39) | TP53TSHRRARBMEN1KMT2A | |
| SCHEMBL9462289 | 0.71 | CHRM2 (0.39) | TP53TSHRRARBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9842607 | 0.71 | CHRM2 (0.38) | TP53TSHRRARBMEN1KMT2A | |
| SCHEMBL463549 | 0.70 | PLA2G2A (0.38) | PLA2G2ATP53TSHRPLA2G4BRARB | |
| SCHEMBL28651335 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101328117-B | 1-phenylalkanecarboxylic acid derivatives for the treatment of neurodegenerative diseases | CHIESI FARMA SPA | 2014-04-23 | — | — | CN | disclosed |
| CN-1984878-B | Derivatives of 1-phenylalkanecarboxylic acids for the treatment of neurodegenerative diseases | CHIESI FARMA SPA | 2011-06-08 | — | — | CN | disclosed |
| CN-101328117-A | 1-phenylalkanecarboxylic acid derivatives for the treatment of neurodegenerative diseases | CHIESI FARMA SPA (IT) | 2008-12-24 | — | — | CN | disclosed |
| CN-100398506-C | 1-phenylalkanecarboxylic acid derivatives for the treatment of neurodegenerative diseases | CHIESI FARMA SPA (IT) | 2008-07-02 | — | — | CN | disclosed |
| CN-1984878-A | Derivatives of 1-phenylalkanecarboxylic acids for the treatment of neurodegenerative diseases | CHIESI FARMA SPA (IT) | 2007-06-20 | — | — | CN | disclosed |
| CN-1751018-A | 1-phenylalkanecarboxylic acid derivatives for the treatment of neurodegenerative diseases | CHIESI FARMA SPA (IT) | 2006-03-22 | — | — | CN | disclosed |