Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 5/20 | 0.38 |
| ▸ | RARB | P10826 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27626499 | 0.70 | PLA2G2A (0.35) | PLA2G2ATP53TSHRPLA2G4BRARB | |
| SCHEMBL9272470 | 0.69 | TP53 (0.33) | PLA2G2ATP53TSHRPLA2G4BMEN1 | |
| SCHEMBL8868294 | 0.64 | THRA (0.33) | PLA2G2ATP53TSHRPLA2G4BMEN1 | |
| SCHEMBL28434026 | 0.62 | MEN1 (0.45) | TP53TSHRPLA2G4BRARBMEN1 | |
| SCHEMBL8532373 | 0.61 | CYP4F2 (0.44) | TSHRMEN1KMT2A | |
| SCHEMBL22335910 | 0.61 | CYP4F2 (0.46) | TSHRMEN1KMT2ATDP1 | |
| SCHEMBL16429168 | 0.59 | PLA2G2A (0.56) | PLA2G2ATP53TSHRPLA2G4BRARB | |
| SCHEMBL10537637 | 0.59 | PLA2G2A (0.56) | PLA2G2ATP53TSHRPLA2G4BRARB | |
| SCHEMBL9863290 | 0.59 | ALDH1A1 (0.57) | TP53TSHR | |
| SCHEMBL5646162 | 0.59 | GPR84 (0.36) | TSHRMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11623022-B2 | Systems and methods for reconstruction of nerve defects | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2023-04-11 | — | — | US | disclosed |
| US-11147904-B2 | Implantable medical devices having double walled microspheres | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2021-10-19 | — | — | US | disclosed |
| EP-3435988-B1 | DRUG-CONTAINING PARTICULATE COMPOSITION WITH CATIONIC AGENT, ASSOCIATED MEDICAL DEVICES, AND METHODS FOR TREATMENT | SURMODICS INC (US) | 2021-10-06 | — | — | EP | disclosed |
| US-11123459-B2 | Hydrophobic active agent particle coatings and methods for treatment | SURMODICS, INC. (US) | 2021-09-21 | — | — | US | disclosed |
| US-20210220866-A1 | COATING SYSTEMS FOR MEDICAL DEVICES | BANK OF MONTREAL, AS COLLATERAL AGENT | 2021-07-22 | — | — | US | disclosed |
| US-11020513-B2 | Insertable medical devices having microparticulate-associated elastic substrates and methods for drug delivery | SURMODICS, INC. (US) | 2021-06-01 | — | — | US | disclosed |
| US-20200368390-A1 | SYSTEMS AND METHODS FOR RECONSTRUCTION OF NERVE DEFECTS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-11-26 | — | — | US | disclosed |
| EP-3554571-A1 | HYDROPHOBIC ACTIVE AGENT PARTICLE COATINGS AND METHODS FOR TREATMENT | Surmodics, Inc. (US) | 2019-10-23 | — | — | EP | disclosed |
| EP-2689789-B1 | Insertable medical devices having microparticulate-associated elastic substrates and methods for drug delivery | SURMODICS INC (US) | 2019-03-13 | — | — | EP | disclosed |
| EP-3436097-A1 | LOCALIZED TREATMENT OF TISSUES THROUGH TRANSCATHETER DELIVERY OF ACTIVE AGENTS | Surmodics, Inc. (US) | 2019-02-06 | — | — | EP | disclosed |
| US-20080020045-A1 | Combination Degradable and Non-Degradable Matrices for Active Agent Delivery | BANK OF MONTREAL, AS COLLATERAL AGENT | 2008-01-24 | — | — | US | disclosed |
| WO-2008008253-A2 | IMPLANTABLE MEDICAL ARTICLES HAVING PRO-HEALING COATINGS | SURMODICS, INC. (US) | 2008-01-17 | — | — | WO | disclosed |
| WO-2008003043-A2 | COMBINATION DEGRADABLE AND NON-DEGRADABLE MATRICES FOR ACTIVE AGENT DELIVERY | SURMODICS, INC. (US) | 2008-01-03 | — | — | WO | disclosed |
| US-20070275027-A1 | Microparticle containing matrices for drug delivery | BANK OF MONTREAL, AS COLLATERAL AGENT | 2007-11-29 | — | — | US | disclosed |
| WO-2007109069-A2 | HYDROPHOBIC DERIVATIVES OF NATURAL BIODEGRADABLE POLYSACCHARIDES AND USES THEREOF | SURMODICS, INC. (US) | 2007-09-27 | — | — | WO | disclosed |
| US-20070224247-A1 | Biodegradable hydrophobic polysaccharide-based drug delivery implants | SURMODICS MD, LLC | 2007-09-27 | — | — | US | disclosed |
| US-20070218102-A1 | Biodegradable hydrophobic polysaccharide-based coatings | SURMODICS, INC. | 2007-09-20 | — | — | US | disclosed |
| WO-2007084418-A2 | MICROPARTICLE CONTAINING MATRICES FOR DRUG DELIVERY | SURMODICS, INC. (US) | 2007-07-26 | — | — | WO | disclosed |
| US-20070128343-A1 | Apparatus And Methods for Applying Coatings | BANK OF MONTREAL, AS COLLATERAL AGENT | 2007-06-07 | — | — | US | disclosed |
| WO-2007059144-A1 | ULTRASONIC NOZZLES FOR APPLYING TWO-COMPONENT COATINGS | SURMODICS, INC. (US) | 2007-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080020045-A1 | Combination Degradable and Non-Degradable Matrices for Active Agent Delivery | MMP1, MMP26, MMP24 | PLA2G2A 925/4885TP53 2173/4885TSHR 4384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.