Methoxymethane

Methoxymethane

SCHEMBL27626992

COC.Cc1cccc(I)c1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.52
ALDH1A1 P00352 2/20 0.42
MAPK1 P28482 1/20 0.42
APP P05067 1/20 0.41
IDO1 P14902 4/20 0.39
RELA Q04206 1/20 0.38
TP53 P04637 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
LMNA P02545 1/20 0.38
NPC1 O15118 1/20 0.37
CASP3 P42574 1/20 0.37
SENP8 Q96LD8 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
MAPT P10636 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1735 0.92
SCHEMBL29669690 0.92
Benzene SCHEMBL28328872 0.90 ACHE (0.58) ACHEALDH1A1MAPK1TP53TDP1
Bromide SCHEMBL3348646 0.90
Fluoride SCHEMBL3562136 0.90 ACHE (0.58) ACHEALDH1A1MAPK1IDO1TP53
Cyanide SCHEMBL28115714 0.85 ACHE (0.52) ACHEALDH1A1MAPK1TP53TDP1
SCHEMBL12428854 0.84 ACHE (0.53) ACHEALDH1A1MAPK1TP53TDP1
M-Xylene SCHEMBL27490026 0.81 ACHE (0.80) ACHEALDH1A1MAPK1IDO1RELA
SCHEMBL17750893 0.78 ACHE (0.50) ACHEALDH1A1MAPK1IDO1NPC1
SCHEMBL21730831 0.76 ACHE (0.48) ACHEALDH1A1MAPK1IDO1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100355710-C Method for preparing aryl iodo substance UNIV SHANGHAI JIAOTONG (CN) 2007-12-19 CN disclosed
CN-1775716-A Method for preparing aryl iodo substance UNIV SHANGHAI JIAOTONG (CN) 2006-05-24 CN disclosed