Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29669690 | 0.97 | — | — | |
| SCHEMBL1735 | 0.97 | — | — | |
| Fluoride SCHEMBL3562136 | 0.94 | ACHE (0.58) | — | |
| Benzene SCHEMBL28328872 | 0.94 | ACHE (0.58) | — | |
| Methoxymethane SCHEMBL27626992 | 0.90 | ACHE (0.52) | — | |
| Cyanide SCHEMBL28115714 | 0.90 | ACHE (0.52) | — | |
| SCHEMBL12428854 | 0.89 | ACHE (0.53) | — | |
| SCHEMBL17750893 | 0.82 | ACHE (0.50) | — | |
| SCHEMBL21730831 | 0.80 | ACHE (0.48) | — | |
| SCHEMBL27466777 | 0.80 | ACHE (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010066357-A1 | BENZOTHIAZOLE AMIDES FOR DETECTION OF AMYLOID BETA | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-06-17 | — | — | WO | disclosed |