SCHEMBL27627345

SCHEMBL27627345

CCc1ccc(C(=O)C(C)(C)Cl)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.55
PLK1 P53350 1/20 0.50
SMN1; SMN2 Q16637 3/20 0.46
HPGD P15428 1/20 0.46
TDP1 Q9NUW8 1/20 0.43
CYP2C19 P33261 2/20 0.43
CYP2C9 P11712 1/20 0.43
NPC1 O15118 2/20 0.42
GAA P10253 2/20 0.42
LMNA P02545 1/20 0.42
POLB P06746 1/20 0.42
AGTR1 P30556 1/20 0.42
TAS1R3 Q7RTX0 1/20 0.42
TAS1R1 Q7RTX1 1/20 0.42
RXRA P19793 1/20 0.42
RXRB P28702 1/20 0.42
MAPT P10636 2/20 0.42
RAB9A P51151 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CYP1A2 P05177 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3682129 0.86 PLK1 (0.40) ALDH1A1PLK1GAAPOLBL3MBTL1
SCHEMBL6687329 0.86 ALDH1A1 (0.57) ALDH1A1PLK1SMN1; SMN2HPGDTDP1
SCHEMBL4009058 0.86 ALDH1A1 (0.57) ALDH1A1PLK1SMN1; SMN2HPGDTDP1
SCHEMBL480674 0.86 KMT2A (0.54) ALDH1A1PLK1CYP2C19LMNARXRA
SCHEMBL1628100 0.83 ALDH1A1 (0.59) ALDH1A1PLK1SMN1; SMN2HPGDTDP1
SCHEMBL12535868 0.82 IDO1 (0.40) ALDH1A1SMN1; SMN2TDP1CYP2C19GAA
SCHEMBL3971183 0.82 ALDH1A1 (0.57) ALDH1A1PLK1SMN1; SMN2HPGDTDP1
SCHEMBL13175610 0.81 ALDH1A1 (0.52) ALDH1A1PLK1SMN1; SMN2HPGDTDP1
SCHEMBL13175931 0.81 ALDH1A1 (0.52) ALDH1A1PLK1SMN1; SMN2HPGDTDP1
SCHEMBL3128806 0.80 ALDH1A1 (0.55) ALDH1A1PLK1SMN1; SMN2HPGDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100523007-C Novel bifunctional photoinitiators CIBA SC HOLDING AG (CH) 2009-08-05 CN disclosed
CN-1668648-A Novel bifunctional photoinitiators CIBA SC HOLDING AG (CH) 2005-09-14 CN disclosed