Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3964785 | 0.86 | ALDH1A1 (0.45) | HPGDALDH1A1KDM4EGAATSHR | |
| SCHEMBL28026626 | 0.85 | ALDH1A1 (0.42) | HPGDMAPK1ALDH1A1KDM4EGAA | |
| SCHEMBL29693696 | 0.79 | KDM4E (0.40) | ALDH1A1KDM4ETSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL4142245 | 0.73 | ALDH1A1 (0.47) | HPGDALDH1A1KDM4EGAATSHR | |
| SCHEMBL8544469 | 0.71 | ALDH1A1 (0.45) | HPGDMAPK1ALDH1A1KDM4EGAA | |
| SCHEMBL18428973 | 0.70 | ALDH1A1 (0.45) | HPGDALDH1A1GAAPOLBSMN1; SMN2 | |
| SCHEMBL865189 | 0.70 | ALDH1A1 (0.47) | HPGDMAPK1ALDH1A1KDM4EGAA | |
| SCHEMBL29006135 | 0.70 | NPC1 (0.45) | HPGDALDH1A1KDM4EGAATSHR | |
| SCHEMBL16470484 | 0.69 | KMT2A (0.41) | ALDH1A1KDM4ETSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL27208468 | 0.68 | AOC3 (0.43) | DHODHKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1671662-A | Piperidine derivatives, process for their preparation and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2005-09-21 | — | — | CN | disclosed |