SCHEMBL4142245

SCHEMBL4142245

O=C(O)N(c1ccccc1)N1CCCCC1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
POLB P06746 1/20 0.47
HPGD P15428 1/20 0.44
KDM4E B2RXH2 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
LMNA P02545 1/20 0.41
HTT P42858 2/20 0.41
GAA P10253 2/20 0.40
USP2 O75604 1/20 0.40
NPSR1 Q6W5P4 1/20 0.39
KMT2A Q03164 6/20 0.39
HSD11B1 P28845 1/20 0.39
MEN1 O00255 2/20 0.38
MAPT P10636 1/20 0.38
TSHR P16473 1/20 0.38
GFER P55789 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8544469 0.98 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2POLBHPGDKDM4E
SCHEMBL18428973 0.85 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2POLBHPGDTDP1
SCHEMBL3964785 0.85 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2POLBHPGDKDM4E
SCHEMBL28026626 0.83 ALDH1A1 (0.42) ALDH1A1SMN1; SMN2POLBHPGDKDM4E
SCHEMBL8779695 0.81 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2POLBHPGDLMNA
SCHEMBL6266552 0.81 SIGMAR1 (0.49) ALDH1A1SMN1; SMN2POLB
SCHEMBL12473807 0.80 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2POLBHPGDKDM4E
SCHEMBL16470484 0.80 KMT2A (0.41) ALDH1A1SMN1; SMN2KDM4ELMNAHTT
SCHEMBL1285362 0.80 ALDH1A1 (0.35) ALDH1A1SMN1; SMN2POLBHPGDKDM4E
SCHEMBL865189 0.78 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2POLBHPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1778229-A4 AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS INCYTE CORP (US) 2009-06-17 EP claimed
EP-1778229-A2 AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS Incyte Corporation (US) 2007-05-02 EP claimed
WO-2006020598-A2 AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS INCYTE CORPORATION (US) 2006-02-23 WO claimed
CN-114929780-B Improved recovery of unreacted diaryl carbonate and process for producing polycarbonate 科思创德国股份有限公司 2024-11-08 CN disclosed
CN-114929780-A Process for producing polycarbonate with improved recovery of unreacted diaryl carbonate 科思创德国股份有限公司 2022-08-19 CN disclosed
WO-2000063356-A2 HERBICIDAL SEED TREATMENT SYNGENTA PARTICIPATIONS AG (CH) 2000-10-26 WO disclosed