Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 15/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6221283 | 0.78 | MAPK14 (0.49) | MAPK14MAPK11MAPK13MAPK12CCNC | |
| SCHEMBL27627755 | 0.76 | MAPK14 (0.45) | MAPK14MAPK11KCNH2MAPK13MAPK12 | |
| SCHEMBL27627754 | 0.76 | MAPK14 (0.45) | MAPK14MAPK11KCNH2MAPK13MAPK12 | |
| SCHEMBL27627894 | 0.74 | MAPK14 (0.44) | MAPK14MAPK11KCNH2MAPK13MAPK12 | |
| SCHEMBL27627887 | 0.74 | MAPK14 (0.44) | MAPK14MAPK11KCNH2MAPK13MAPK12 | |
| SCHEMBL27627774 | 0.74 | PTGDR2 (0.43) | MAPK14MAPK11MAPK13MAPK12ALOX5 | |
| SCHEMBL27608554 | 0.70 | MAPK14 (0.46) | MAPK14MAPK11KCNH2MAPK13MAPK12 | |
| SCHEMBL27608556 | 0.69 | MAPK14 (0.52) | MAPK14MAPK11MAPK13MAPK12 | |
| SCHEMBL2662514 | 0.66 | MAPK14 (0.47) | MAPK14MAPK11MAPK13MAPK12GCGR | |
| SCHEMBL6377962 | 0.65 | HTR3A (0.47) | MAPK14MAPK11MAPK13MAPK12CCNC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1701069-A | 3,4-disubstituted pyrroles and their for use in treating inflammatory diseases | JANSSEN PHARMACEUTICA NV (BE) | 2005-11-23 | — | — | CN | disclosed |