Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4492046 | 0.88 | CHRM1 (0.44) | CHRM1LMNAALDH1A1HTTPOLB | |
| SCHEMBL3588954 | 0.76 | ALDH1A1 (0.59) | LMNAALDH1A1MEN1POLBMAPT | |
| SCHEMBL3314468 | 0.76 | ALDH1A1 (0.59) | LMNAALDH1A1MEN1POLBMAPT | |
| SCHEMBL788760 | 0.71 | — | — | |
| SCHEMBL3179327 | 0.71 | ALDH1A1 (0.46) | LMNAALDH1A1MAPK1MEN1MAPT | |
| SCHEMBL1434475 | 0.71 | ALDH1A1 (0.46) | LMNAALDH1A1MAPK1MEN1MAPT | |
| SCHEMBL15431899 | 0.69 | CYP1A2 (0.48) | CHRM1 | |
| SCHEMBL20434091 | 0.69 | CYP1A2 (0.48) | CHRM1 | |
| SCHEMBL2908533 | 0.69 | CHRM1 (0.49) | CHRM1LMNAALDH1A1HTT | |
| SCHEMBL12668009 | 0.69 | CA12 (0.52) | CHRM1ALDH1A1MAPK1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1774435-A | 5-membered heterocyclic derivative | DAIICHI SEIYAKU CO (JP) | 2006-05-17 | — | — | CN | disclosed |