Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 4/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP7 | P09237 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27627809 | 0.88 | CHRM1 (0.36) | CHRM1POLBCA1CA2CA9 | |
| SCHEMBL2379763 | 0.81 | CHRM1 (0.49) | CHRM1GSK3BDYRK1ACYP1A2TDP1 | |
| SCHEMBL2901294 | 0.81 | CHRM1 (0.49) | CHRM1GSK3BDYRK1ACYP1A2TDP1 | |
| SCHEMBL17625631 | 0.81 | CYP1A2 (0.48) | CHRM1GSK3BDYRK1ACYP1A2TDP1 | |
| SCHEMBL20434091 | 0.81 | CYP1A2 (0.48) | CHRM1GSK3BDYRK1ACYP1A2TDP1 | |
| SCHEMBL15431899 | 0.81 | CYP1A2 (0.48) | CHRM1GSK3BDYRK1ACYP1A2TDP1 | |
| SCHEMBL2908533 | 0.81 | CHRM1 (0.49) | CHRM1GSK3BDYRK1ACYP1A2TDP1 | |
| Hydrochloric Acid SCHEMBL28577066 | 0.79 | CHRM1 (0.48) | CHRM1GSK3BDYRK1ACYP1A2TDP1 | |
| SCHEMBL21884827 | 0.79 | CHRM1 (0.44) | CHRM1GSK3BDYRK1ACYP1A2TDP1 | |
| SCHEMBL28577061 | 0.79 | CHRM1 (0.44) | CHRM1GSK3BDYRK1ACYP1A2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638523-B2 | Diarylamine-containing compounds and compositions, and their use as modulators of c-kit receptors | IRM LLC (BM) | 2009-12-29 | — | — | US | disclosed |
| CN-1759110-A | Pyrazole derivatives | DAIICHI SEIYAKU CO (JP) | 2006-04-12 | — | — | CN | disclosed |