Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA3 | P32297 | 3/20 | 0.67 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.63 |
| ▸ | HTR3A | P46098 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4429334 | 0.94 | CHRNA3 (0.59) | CHRNA3CHRNA7HTR3A | |
| SCHEMBL2763026 | 0.85 | CHRNA3 (0.68) | CHRNA3CHRNA7HTR3A | |
| SCHEMBL2763192 | 0.83 | CHRNA3 (0.65) | CHRNA3CHRNA7HTR3A | |
| SCHEMBL2762690 | 0.83 | CHRNA3 (0.45) | CHRNA3CHRNA7HTR3A | |
| SCHEMBL5914764 | 0.80 | CHRNA3 (1.00) | CHRNA3CHRNA7HTR3A | |
| SCHEMBL7559030 | 0.78 | CHRNA7 (1.00) | CHRNA3CHRNA7HTR3A | |
| SCHEMBL2908050 | 0.76 | CHRNA7 (0.89) | CHRNA3CHRNA7HTR3A | |
| SCHEMBL7556223 | 0.76 | CHRNA7 (0.84) | CHRNA3CHRNA7HTR3A | |
| SCHEMBL4190184 | 0.76 | CHRNA7 (0.78) | CHRNA3CHRNA7HTR3A | |
| SCHEMBL5914683 | 0.76 | CHRNA7 (0.78) | CHRNA3CHRNA7HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029594-B1 | NOVEL 1,4-DIAZA-BICYCLO[3.2.2]NONANE DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH AS (DK) | 2010-10-20 | — | — | EP | claimed |
| US-20090118265-A1 | NOVEL 1,4-DIAZA-BICYCLO[3.2.2]NONANE DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH A/S (DK) | 2009-05-07 | — | — | US | claimed |
| EP-2029594-B1 | NOVEL 1,4-DIAZA-BICYCLO[3.2.2]NONANE DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH AS (DK) | 2010-10-20 | — | — | EP | disclosed |
| US-20090118265-A1 | NOVEL 1,4-DIAZA-BICYCLO[3.2.2]NONANE DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH A/S (DK) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118265-A1 | NOVEL 1,4-DIAZA-BICYCLO[3.2.2]NONANE DERIVATIVES AND THEIR MEDICAL USE | CHRNA2, CHRNA3, CHRNA10 | CHRNA3 2/4885CHRNA7 6/4885HTR3A 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.