Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL836615 | 0.83 | TRPA1 (0.44) | ALDH1A1KDM4EHPGDTRPA1SMN1; SMN2 | |
| SCHEMBL836614 | 0.83 | TRPA1 (0.44) | ALDH1A1KDM4EHPGDTRPA1SMN1; SMN2 | |
| SCHEMBL2762834 | 0.80 | TRPA1 (0.52) | GAAALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL2762968 | 0.78 | SLC6A2 (0.64) | ALDH1A1HPGDTRPA1SMN1; SMN2NPC1 | |
| SCHEMBL27790399 | 0.78 | SLC6A2 (0.64) | ALDH1A1HPGDTRPA1SMN1; SMN2NPC1 | |
| SCHEMBL16256023 | 0.76 | HPGD (0.41) | ALDH1A1KDM4EMAPTHPGDTRPA1 | |
| SCHEMBL30695656 | 0.76 | TRPA1 (0.45) | GAAALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL3401824 | 0.75 | TP53 (0.45) | GAAALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL30695639 | 0.75 | TP53 (0.45) | GAAALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL3843873 | 0.75 | NR1H4 (0.54) | GAAALDH1A1KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247337-A | Method for asymmetrically synthesizing 1, 2-trans-amino alcohol and derivative thereof | 凯特立斯（深圳）科技有限公司 | 2023-12-19 | — | — | CN | disclosed |
| EP-2173728-A2 | HETEROCYCLIC MODULATORS OF PKB | Amgen Inc. (US) | 2010-04-14 | — | — | EP | disclosed |
| WO-2009011880-A2 | HETEROCYCLIC MODULATORS OF PKB | AMGEN INC. (US) | 2009-01-22 | — | — | WO | disclosed |