Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 5/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.41 |
| ▸ | CHRNG | P07510 | 2/20 | 0.41 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | CHRND | Q07001 | 2/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18660862 | 0.86 | PPARG (0.49) | TRPA1PPARGPPARAALDH1A1MAPT | |
| SCHEMBL27405397 | 0.86 | MIF (0.46) | TRPA1PPARGPPARAMAPTGAA | |
| SCHEMBL18660861 | 0.86 | PPARG (0.49) | TRPA1PPARGPPARAALDH1A1MAPT | |
| SCHEMBL27405399 | 0.86 | MIF (0.46) | TRPA1PPARGPPARAMAPTGAA | |
| SCHEMBL24298844 | 0.85 | HDAC1 (0.45) | TRPA1PPARGPPARAALDH1A1MAPT | |
| SCHEMBL2791437 | 0.85 | ALDH1A1 (0.49) | TRPA1ALDH1A1MAPTLMNATSHR | |
| SCHEMBL21180491 | 0.85 | TRPA1 (0.48) | TRPA1PPARGPPARAALDH1A1MAPT | |
| SCHEMBL18660710 | 0.85 | ALDH1A1 (0.49) | TRPA1ALDH1A1MAPTLMNATSHR | |
| SCHEMBL24298843 | 0.85 | HDAC1 (0.45) | TRPA1PPARGPPARAALDH1A1MAPT | |
| SCHEMBL3871050 | 0.85 | TRPA1 (0.48) | TRPA1PPARGPPARAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247337-A | Method for asymmetrically synthesizing 1, 2-trans-amino alcohol and derivative thereof | 凯特立斯（深圳）科技有限公司 | 2023-12-19 | — | — | CN | disclosed |
| EP-2173728-A2 | HETEROCYCLIC MODULATORS OF PKB | Amgen Inc. (US) | 2010-04-14 | — | — | EP | disclosed |
| WO-2009011880-A2 | HETEROCYCLIC MODULATORS OF PKB | AMGEN INC. (US) | 2009-01-22 | — | — | WO | disclosed |