Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3837666 | 0.85 | CA1 (0.41) | CA2PTGES2HTR2ACA12CA1 | |
| SCHEMBL6062879 | 0.85 | CA2 (0.45) | CA2SMN1; SMN2CA12CA1CA9 | |
| SCHEMBL6121437 | 0.84 | CA1 (0.45) | CA2PTGES2HTR2ACA12CA1 | |
| SCHEMBL5514013 | 0.81 | CA2 (0.41) | CA2SMN1; SMN2CA12CA1CA9 | |
| SCHEMBL31344740 | 0.81 | BID (0.46) | CA2SMN1; SMN2CA12CA1CA9 | |
| SCHEMBL10946601 | 0.81 | BID (0.41) | SMN1; SMN2CNR2CNR1TLR8 | |
| SCHEMBL3837671 | 0.81 | CA1 (0.42) | CA2PTGES2CA12CA1CA9 | |
| SCHEMBL579011 | 0.80 | BID (0.47) | CA2 | |
| SCHEMBL6714375 | 0.80 | CA2 (0.45) | CA2SMN1; SMN2CA12CA1CA9 | |
| SCHEMBL8095518 | 0.79 | TLR8 (0.44) | HTR2ATLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1768050-A | Benzopyran compounds for the treatment of inflammation | PHARMACIA CORP (US) | 2006-05-03 | — | — | CN | disclosed |