Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | LDHB | P07195 | 1/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095162 | 0.95 | TLR8 (0.49) | TLR8HTR2ALIPGSIGMAR1CYSLTR2 | |
| SCHEMBL8087327 | 0.93 | LIPG (0.49) | TLR8LIPGCYSLTR2CYSLTR1 | |
| SCHEMBL8100321 | 0.93 | LIPG (0.49) | TLR8LIPGCYSLTR2CYSLTR1 | |
| SCHEMBL8102396 | 0.93 | LIPG (0.49) | TLR8LIPGCYSLTR2CYSLTR1 | |
| Phenol SCHEMBL28085339 | 0.92 | DRD2 (0.43) | TLR8LMNAHTTLDHALDHB | |
| SCHEMBL8087736 | 0.89 | TLR8 (0.43) | TLR8HTR2ALMNAHTTLIPG | |
| SCHEMBL2049765 | 0.87 | SIGMAR1 (0.44) | TLR8HTTLIPGSIGMAR1HSD11B1 | |
| SCHEMBL10918220 | 0.87 | LIPG (0.41) | TLR8HTTLIPGCYSLTR2CYSLTR1 | |
| Phenol SCHEMBL28176922 | 0.86 | BID (0.47) | TLR8LMNALIPGCYSLTR2CYSLTR1 | |
| SCHEMBL6546504 | 0.86 | TLR8 (0.44) | TLR8HTR2ALMNAHTTLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |