Methylamine

Methylamine

SCHEMBL27628958

CC(=O)Oc1ccn[nH]1.CN.CN.CN

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.39
LMNA P02545 3/20 0.35
NPC1 O15118 4/20 0.35
RAB9A P51151 4/20 0.35
PKM P14618 3/20 0.35
POLB P06746 2/20 0.35
ALOX15 P16050 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
TP53 P04637 1/20 0.35
USP2 O75604 1/20 0.34
HRH2 P25021 1/20 0.34
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
ACHE P22303 2/20 0.33
MAPT P10636 1/20 0.32
SLC22A6 Q4U2R8 1/20 0.32
CDK2 P24941 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ELANE P08246 1/20 0.32
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27439148 0.96
SCHEMBL15716188 0.80
SCHEMBL2363165 0.78
SCHEMBL28111228 0.76 PKM (0.43) HCAR2LMNANPC1RAB9APKM
SCHEMBL8719841 0.73 PKM (0.48) HCAR2PKMPOLBMAPTKDM4E
SCHEMBL28317948 0.72 HCAR2 (0.38) HCAR2NPC1RAB9APKMALOX15
SCHEMBL1763751 0.72 PKM (0.37) HCAR2NPC1RAB9APKMCYP3A4
SCHEMBL10801840 0.70 NPC1 (0.51) HCAR2LMNANPC1RAB9APKM
SCHEMBL4276190 0.68 LMNA (0.44) LMNARAB9APKMPOLBACHE
SCHEMBL7199146 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101284814-B Method for producing acrylonitrile compound NISSAN CHEMICAL IND LTD 2011-08-17 CN disclosed
CN-101891682-A The manufacture method of acrylonitrile compound NISSAN CHEMICAL IND LTD 2010-11-24 CN disclosed
CN-101284814-A Method for producing acrylonitrile compound NISSAN CHEMICAL IND LTD (JP) 2008-10-15 CN disclosed
CN-100402503-C Method for producing acrylonitrile compound NISSAN CHEMICAL IND LTD (JP) 2008-07-16 CN disclosed
CN-1768042-A Method for producing acrylonitrile compound NISSAN CHEMICAL IND LTD (JP) 2006-05-03 CN disclosed